FITC标记的癌症亮氨酸拉链下调因子1抗体上海沪震实业有限公司

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产品名称: FITC标记的癌症亮氨酸拉链下调因子1抗体
英文名称: Anti-LDOC1/FITC
抗体货号: HZ-6543R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: IF=1:50-200
更新时间: 2018/9/22 10:32:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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200612
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上海·中国-上海
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产品详细描述

 Rabbit Anti-LDOC1/FITC Conjugated antibody

FITC标记的癌症亮氨酸拉链下调因子1抗体

 

英文名称 Anti-LDOC1/FITC
中文名称 FITC标记的癌症亮氨酸拉链下调因子1抗体
别    名 BCUR1; Breast cancer up regulated 1; Breast cancer upregulated 1; Gm366; Leucine zipper down regulated in cancer 1; Leucine zipper protein down regulated in cancer cells; Leucine zipper protein down regulated in cancer cells; Mar7; Mart7; Protein LDOC1; RGD1565644; LDOC1_HUMAN .  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  染色质和核信号  信号转导  转录调节因子  肿瘤细胞生物标志物  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Dog, Pig, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LDOC1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]. 

Function:
May have an important role in the development and/or progression of some cancers.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitously expressed with high levels in brain and thyroid and low expression in placenta, liver and leukocytes. Expressed as well in six of the seven human breast cancer cell lines examined.

Similarity:
Belongs to the LDOC1 family.

Database links:

Entrez Gene: 23641 Human

Omim: 300402 Human

SwissProt: O95751 Human

Unigene: 45231 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

由该基因编码的蛋白质包含亮氨酸拉链状基序和富含脯氨酸的区域,其与SH3结合结构域具有显著的相似性。蛋白质定位于细胞核,在某些癌细胞系中被下调。它被认为是调节核转录因子-κB(NF-kappaB)介导的转录应答。该基因已被提出作为肿瘤抑制基因,其蛋白产物可能在一些癌症的发展和/或进展中具有重要的作用。[ RefSeq,JUL 2008 ]提供。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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