FITC标记的同源盒蛋白B8抗体
产品名称： FITC标记的同源盒蛋白B8抗体
英文名称： Anti-HOXB8/FITC
产品编号： HZ-6539R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-HOXB8/FITC Conjugated antibody
FITC标记的同源盒蛋白B8抗体
| 英文名称 | Anti-HOXB8/FITC |
| 中文名称 | FITC标记的同源盒蛋白B8抗体 |
| 别 名 | Homeobox B8; Homeobox protein Hox B8; Homeobox protein HoxB8; HOX 2; Hox 2.4; HOX 2D; HOX B8; HOX2; Hox2.4; HOX2D; HOXB8; HXB8_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 染色质和核信号 信号转导 干细胞 转录调节因子 细胞表面分子 肿瘤细胞生物标志物 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 28kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HOXB8 (1-50aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania. Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Subcellular Location: Nucleus. Similarity: Belongs to the Antp homeobox family. Contains 1 homeobox DNA-binding domain. Database links: UniProtKB/Swiss-Prot: P17481.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因是ANTP同源盒家族的成员，编码同源核DNA结合域的核蛋白。它包含在位于17号染色体上的同源盒B基因簇中。编码的蛋白质作为参与发育的序列特异性转录因子。该基因的表达增加与结直肠癌相关。小鼠已敲除该基因的小鼠同源基因表现出过度的病理疏导行为。这种行为类似于患有强迫症性手足徐动症的人的行为。