FITC标记的细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体上海沪震实业有限公司

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产品名称: FITC标记的细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体
英文名称: Anti-FOLH1B/FITC
抗体货号: HZ-6535R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: IF=1:50-200
更新时间: 2018/7/13 11:09:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Rabbit Anti-FOLH1B/FITC Conjugated antibody

FITC标记的细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体

 

英文名称 Anti-FOLH1B/FITC
中文名称 FITC标记的细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体
别    名 PSMAL; Cell growth inhibiting gene 26 protein; Folate hydrolase 1B; Folate hydrolase 2; Folate hydrolase pseudogene; FOLH2; FOLHP; GCP3; GCPIII; glutamate carboxypeptidase III; N acetylated alpha linked acidic dipeptidase; NAALADase; Prostate specific membrane antigen like protein; PSM; PSMA like; Putative folate hydrolase 1B; Putative N acetylated alpha linked acidic dipeptidase; FOH1B_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  信号转导  肿瘤细胞生物标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FOLH1B (181-225aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Prostate cancer is the most frequently diagnosed cancer and the early detection of prostate cancer dramatically and efficiently reduces the observed mortality rate. Several proteins have been identified as specific markers of prostate cancer, and they may be useful as diagnostic indicators. PSA, prostate specific antigen, is the classical indicator for transformed prostate tissue; however, in addition to being upregulated in prostate cancer, PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia prostate. Conversely, STEAP (six-transmembrane epithelial antigen of the prostate), prostate carcinoma tumor antigen (PCTA-1) and prostate-specific membrane antigen (PSM) represent additional prostate-specific antigens that are overexpressed only in malignant tumors and therefore are more specific identifiers of malignancies. PSM is an integral membrane protein, and PCTA-1 is related to the galectin gene family, which mediate both cell-cell and cell-matrix interactions in a manner similar to the selectin subgroup of C-type lectins. STEAP is a serpentine transmembrane cell-surface tumor-antigen that is predicted to functions as a channel or transporter protein. In addition to prostate cancers, STEAP is also upregulated in bladder, colon and ovarian cancers.

Function:
Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity.
Exhibits a dipeptidyl-peptidase IV type activity.

Subcellular Location:
Cytoplasm

Tissue Specificity:
Kidney and liver. Not expressed in the prostate.

Similarity:
Belongs to the peptidase M28 family. M28B subfamily.

Database links:

Entrez Gene: 219595 Human

Omim: 609020 Human

SwissProt: Q9HBA9 Human

Unigene: 645352 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

前列腺癌是最常见的诊断癌症,早期发现前列腺癌显著且有效地降低了观察到的死亡率。几种蛋白质已被确定为前列腺癌的特异性标志物,它们可能是有用的诊断指标。PSA,前列腺特异性抗原,是前列腺癌转化组织的经典指标;然而,除了前列腺癌的上调,PSA也在非恶性疾病如良性前列腺增生前列腺中上调。相反,STEAP(前列腺六跨膜上皮抗原)、前列腺癌肿瘤抗原(PCTA-1)和前列腺特异性膜抗原(PSM)代表仅在恶性肿瘤中过表达的附加前列腺特异性抗原,因此更具体的标识符。恶性肿瘤。PSM是一种完整的膜蛋白,PCTA-1与半乳糖凝集素基因家族相关,其介导的细胞-细胞和细胞-基质相互作用的方式与C型凝集素的选择子亚基相似。STEAP是一种蜿蜒跨膜细胞表面肿瘤抗原,被预测为起到通道或转运蛋白的作用。除了前列腺癌外,STEAP在膀胱癌、结肠癌和卵巢癌中也有上调。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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