FITC标记的细胞表面趋化因子受体5抗体上海沪震实业有限公司

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产品名称: FITC标记的细胞表面趋化因子受体5抗体
英文名称: Anti-CXCR5/FITC
抗体货号: HZ-3598R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: KLH conjugated synthetic peptide derived from human CXCR5/CD185
更新时间: 2018/8/9 9:36:00
详细资料:  实验方法技术资料
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诚信指数:1030点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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021-60345367
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陈先生
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上海·中国-上海
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产品详细描述

 Rabbit Anti-CXCR5/FITC Conjugated antibody

FITC标记的细胞表面趋化因子受体5抗体

 

英文名称 Anti-CXCR5/FITC
中文名称 FITC标记的细胞表面趋化因子受体5抗体
别    名 BLR 1; BLR1; Burkitt lymphoma receptor 1; Burkitt lymphoma receptor 1 GTP binding protein; C X C chemokine receptor type 5; C-X-C chemokine receptor type 5; CD 185; CD185; CD185 antigen; Chemokine C X C motif receptor 5; Chemokine CXC motif receptor 5; Chemokine receptor 5; CXC chemokine receptor type 5; CXC R5; CXC-R5; CXCR 5; CXCR-5; Cxcr5; CXCR5_HUMAN; MDR 15; MDR-15; MDR15; MGC117347; Monocyte derived receptor 15; Monocyte-derived receptor 15.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  信号转导  趋化因子  G蛋白偶联受体  b-淋巴细胞  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Rabbit, 
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CXCR5/CD185
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The CXCR5 gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. CXCR5 protein is predicted to be a seven transmembrane G protein coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of the gene and its mouse conterpart strongly suggest the essential function of the protein is in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen.

Function:
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. 

Subcellular Location:
Cell membrane; Multi-pass membrane protein. 

Tissue Specificity:
Expression in mature B-cells and Burkitt lymphoma cells.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 643 Human

Entrez Gene: 12145 Mouse

Entrez Gene: 29363 Rat

Omim: 601613 Human

SwissProt: P32302 Human

SwissProt: Q04683 Mouse

SwissProt: P34997 Rat

Unigene: 113916 Human

Unigene: 490637 Mouse

Unigene: 6246 Mouse

Unigene: 120732 Rat

Unigene: 127121 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

CXCR5基因是在Burkitt淋巴瘤和淋巴组织中特异表达的基因。CXCR5蛋白是一种七跨膜G蛋白偶联受体,属于CXC趋化因子受体家族。B淋巴细胞趋化因子BLC是该受体的特异性配体。对该基因及其小鼠的研究表明,该蛋白的基本功能是在特定的解剖室中的B细胞迁移和定位,如淋巴结和脾脏中的卵泡。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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