FITC标记的联会复合体蛋白3抗体
产品名称： FITC标记的联会复合体蛋白3抗体
英文名称： Anti-CTDSPL/FITC
产品编号： HZ-3509R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-CTDSPL/FITC Conjugated antibody
FITC标记的联会复合体蛋白3抗体
| 英文名称 | Anti-CTDSPL/FITC |
| 中文名称 | FITC标记的联会复合体蛋白3抗体 |
| 别 名 | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; CTD small phosphatase-like protein; CTDSL_HUMAN; CTDSP-like; Ctdspl; hYA22; NIF-like protein; NLI-interacting factor 1; Nuclear LIM interactor-interacting factor 1; Protein YA22; RBSP3; SCP3; Small C-terminal domain phosphatase 3; Small CTD phosphatase 3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 发育生物学 细胞周期蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SCP3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: During meiosis, the homologous chromosomes pair and recombine, a process essential for generating genetically distinct haploid cells. The unique behavior displayed by meiotic chromosomes has been linked to the activities of a meiosis-specific supramolecular proteinaceous structure, the synaptonemal complex (SC). Three meiosis-specific components of the SC have been characterized in mammals, SCP1, SCP2 and SCP3. SCP3 has a C-terminal coiled-coil domain that has been shown to promote homotypic interactions in vitro. Function: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. Subunit: Monomer. Interacts with REST. Subcellular Location: Nucleus. Tissue Specificity: Expression is restricted to non-neuronal tissues. Similarity: Contains 1 FCP1 homology domain. Database links: Entrez Gene: 10217 Human Entrez Gene: 69274 Mouse Omim: 608592 Human SwissProt: O15194 Human SwissProt: P58465 Mouse Unigene: 475963 Human Unigene: 439928 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
减数分裂过程中，同源染色体对并重组，这是产生基因单倍体细胞必不可少的过程。减数分裂染色体显示的独特行为与减数分裂特异性超分子蛋白结构，联会复合体（SC）的活动有关。在哺乳动物中，三个减数分裂的特异性成分已被鉴定为SCP1、SCP2和SCP3。SCP3具有C-末端卷曲螺旋结构域，已被证明在体外促进同型相互作用。