FITC标记的金属离子转运体1抗体
产品名称： FITC标记的金属离子转运体1抗体
英文名称： Anti-DMT1/FITC
产品编号： HZ-3577R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： Flow-Cyt=1:50-200 IF=1:50-200
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Rabbit Anti-DMT1/FITC Conjugated antibody
FITC标记的金属离子转运体1抗体
| 英文名称 | Anti-DMT1/FITC |
| 中文名称 | FITC标记的金属离子转运体1抗体 |
| 别 名 | DCT 1; DCT1; Divalent metal transporter 1; DMT 1; DMT1; Natural resistance associated macrophage protein 2; NRAMP 2; NRAMP2; NRAM2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, |
| 产品应用 | Flow-Cyt=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 62kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DMT1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: DMT1 is a major transporter of ferrous iron from the intestinal lumen. DMT1 belongs to the family of NRAMP metal ion transporters which function in diverse organisms from bacteria to human. DMT1 (NRAMP2) transports metal ions at the plasma membrane of cells of both the duodenum and in peripheral tissues, and defective DMT1 causes anaemia. Function: Actin-bundling protein. May function in mitogen-activated protein kinase pathway. Subcellular Location: Cytoplasm. Tissue Specificity: Heart, brain, lung, skeletal muscle, and kidney. Post-translational modifications: Actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase. Similarity: Belongs to the villin/gelsolin family. Contains 1 HP (headpiece) domain. Database links: Entrez Gene: 4891 Human Entrez Gene: 18174 Mouse Omim: 600523 Human SwissProt: P49281 Human SwissProt: P49282 Mouse Unigene: 505545 Human Unigene: 234608 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
DMT1是铁离子从肠腔中转运的主要载体。DMT1属于NRAMP金属离子转运蛋白家族，在多种生物体中发挥作用，从细菌到人。DMT1（NRAMP2）在十二指肠和周围组织细胞膜上转运金属离子，DMT1缺陷导致贫血。