FITC标记的阶段特异性胚胎表面抗原-3抗体
产品名称： FITC标记的阶段特异性胚胎表面抗原-3抗体
英文名称： Anti-SSEA3/FITC
产品编号： HZ-3575R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-SSEA3/FITC Conjugated antibody
FITC标记的阶段特异性胚胎表面抗原-3抗体
| 英文名称 | Anti-SSEA3/FITC |
| 中文名称 | FITC标记的阶段特异性胚胎表面抗原-3抗体 |
| 别 名 | B3GT5_MOUSE; Beta-1,3-galactosyltransferase 5; Beta-1,3-GalTase 5; Beta3Gal-T5; Beta3GalT5; b3Gal-T5; Beta-3-Gx-T5 Stage-specific embryonic antigen 3 synthase; SSEA-3 synthase; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 干细胞 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 36kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | 4-8 cell stage mouse embryos. |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: SSEA3 is a globoseries carbohydrate antigen present on both cell surface glycolipids and glycopeptides. It is found on the surface of mouse oocytes, becoming restricted to the intracellular mass of the early blastocyst and then to the primitive endoderm. It is present on the surface of human teratocarcinoma cells (EC), embryonic germ cells (EG) and embryonic stem cells (ES) but not mouse undifferentiated mouse cells of these types. SSEA3 expression decreases as human EC, ES and EG cells differentiate but increases on differentiation of mouse EC, ES and EG cells. It is also found on the surface of mouse erythrocytes. Function: Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor. Also catalyzes the transfer of Gal to the terminal GalNAc unit of the globoside GB4, thereby synthesizing the glycolipid GB5, also known as the stage-specific embryonic antigen-3 (SSEA-3). Subcellular Location: Golgi apparatus membrane; Single-pass type II membrane protein (Potential). Tissue Specificity: Expressed in brain and kidney. Similarity: Belongs to the glycosyltransferase 31 family. Database links:
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
SSEA3是一种存在于细胞表面糖脂和糖肽上的球形糖蛋白抗原。它在小鼠卵母细胞表面发现，被限制在早期胚泡的细胞内，然后局限于原始内胚层。它存在于人畸胎瘤细胞（EC）、胚胎生殖细胞（EG）和胚胎干细胞（ES）的表面上，但不存在于这些类型的小鼠未分化的小鼠细胞上。SSEA3的表达随着人EC、ES和EG细胞的分化而降低，但在小鼠EC、ES和EG细胞分化中增加。在小鼠红细胞表面也可见。