FITC标记的受体结合丝氨酸苏氨酸激酶2抗体上海沪震实业有限公司

性能参数

产品名称: FITC标记的受体结合丝氨酸苏氨酸激酶2抗体
英文名称: Anti-RIP2/FITC
抗体货号: HZ-3546R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: IF=1:50-200
更新时间: 2018/8/9 13:45:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-RIP2/FITC Conjugated antibody 

FITC标记的受体结合丝氨酸苏氨酸激酶2抗体

 

英文名称 Anti-RIP2/FITC
中文名称 FITC标记的受体结合丝氨酸苏氨酸激酶2抗体
别    名 Receptor interacting protein 2; Receptor interacting serine threonine kinase 2; Receptor interacting serine/threonine protein kinase 2; RICK; RIP 2; RIP LIKE INTERACTING CLARP KINASE; RIPK 2; RIPK2; TNFRSF; CARD 3; CARD carrying kinase; CARD CONTAINING ICE ASSOCIATED KINASE; CARD containing IL 1 beta ICE kinase; CARD containing IL1 beta ICE kinase; CARD containing interleukin 1 beta converting enzyme (ICE) associated kinase; CARD containing interleukin 1 beta converting enzyme associated kinase; CARD3; CARDIAK; CCK; CLARP kinase; GIG 30; GIG30 ; Growth inhibiting gene 30; Receptor interacting protein (RIP) like interacting caspase like apoptosis regulatory protein (CLARP) kinase.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Guinea Pig, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RIP2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
RIP2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. It contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.

Function:
Activates pro-caspase-1 and pro-caspase-8. Potentiates CASP8-mediated apoptosis. Activates NF-kappa-B.

Subunit:
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Contains 1 CARD domain. Contains 1 protein kinase domain.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Detected in heart, brain, placenta, lung, peripheral blood leukocytes, spleen, kidney, testis, prostate, pancreas and lymph node.

Post-translational modifications:
Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR. Ubiquitinated; undergoes 'Lys-63'-linked polyubiquitination catalyzed by ITCH.

Similarity:
Belongs to the protein kinase superfamily.
TKL Ser/Thr protein kinase family.
Contains 1 CARD domain.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 8767 Human

Entrez Gene: 192656 Mouse

Entrez Gene: 362491 Rat

Omim: 603455 Human

SwissProt: O43353 Human

SwissProt: P58801 Mouse

Unigene: 103755 Human

Unigene: 112765 Mouse

Unigene: 102179 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

受体结合丝氨酸苏氨酸激酶2又称受体相互作用蛋白2
   
   

RIP2是丝氨酸/苏氨酸蛋白激酶受体相互作用蛋白(RIP)家族的成员。它含有C-末端caspase活化和募集结构域(CARD),是先天和适应性免疫途径中信号复合物的一个组成部分。它是一种有效的NF-κB活化剂,是诱导多种细胞刺激的细胞凋亡的诱导剂。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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