FITC标记的磷酸化内分泌腺衍生血管内皮生长因子抗体上海沪震实业有限公司

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产品名称: FITC标记的磷酸化内分泌腺衍生血管内皮生长因子抗体
英文名称: Anti-Phospho-PRK1 (Thr774) + PRK2 (Thr816) + PRK3 (Thr718)/FITC
抗体货号: HZ-3347R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: IF=1:50-200
更新时间: 2018/8/9 14:19:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-Phospho-PRK1 (Thr774) + PRK2 (Thr816) + PRK3 (Thr718)/FITC Conjugated antibody 

FITC标记的***酸化内分泌腺衍生血管内皮生长因子抗体

 

英文名称 Anti-Phospho-PRK1 (Thr774) + PRK2 (Thr816) + PRK3 (Thr718)/FITC
中文名称 FITC标记的***酸化内分泌腺衍生血管内皮生长因子抗体
别    名 PRK3+PRK2+PRK1 (phospho T816 + T718 + T774); PROK1; Prokineticin-1/Endocrine-gland-derived vascular endothelial growth factor; EGVEGF; PK1; EG-VEGF; EG VEGF; PRK1; Prokineticin 1; Black mamba toxin related; Endocrine gland derived vascular endothelial growth factor; Endocrine-gland-derived vascular endothelial growth factor; Mambakine; PROK1_HUMAN; Cardiolipin activated protein kinase Pak2; PAK 2; PAK2; PKN gamma; PKN2; PKN2_HUMAN; PRK2; PRKCL2; PRO2042; Protein kinase C like 2; Protein kinase C related kinase 2; Protein kinase C-like 2; Protein kinase N2; Protein-kinase C-related kinase 2; Serine/threonine-protein kinase N2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 ***酸化抗体 
研究领域 肿瘤  免疫学  血管内皮细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 103kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human PRK1 around the phosphorylation site of Thr774
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner. [provided by RefSeq, Sep 2011]

Function:
Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.

Subcellular Location:
Secreted.

Tissue Specificity:
Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta.

Similarity:
Belongs to the AVIT (prokineticin) family.

Database links:

Entrez Gene: 84432 Human

Entrez Gene: 246691 Mouse

Entrez Gene: 192205 Rat

Omim: 606233 Human

SwissProt: P58294 Human

SwissProt: Q14A28 Mouse

SwissProt: Q8R414 Rat

Unigene: 514793 Human

Unigene: 461353 Mouse

Unigene: 82757 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

EG-VEGF是先被发现的组织特异性促血管生成因子,与多种特定组织肿瘤的发生及演进相关,EG-VEGF多在卵巢、睾丸、肾上腺、胎盘等类固醇合成组织中高表达

由该基因编码的蛋白质诱导来自内分泌腺的毛细血管内皮细胞的增殖、迁移和开窗(膜不连续性的形成)。它对多种其他内皮细胞和非内皮细胞类型几乎没有或没有影响。它的表达仅限于类固醇生成腺(卵巢、睾丸、肾上腺和胎盘),是由缺氧诱导的,并且常常与血管内皮生长因子(VEGF)的表达互补,提示这些分子以协调的方式发挥作用。[ RefSeq,SEP 2011提供]

 

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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