FITC标记的磷酸化果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体-抗体-抗体-生物在线
FITC标记的磷酸化果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体

FITC标记的磷酸化果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体

商家询价

产品名称: FITC标记的磷酸化果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体

英文名称: Anti-Phospho-PFKFB3/PFK2 (Ser467)/FITC

产品编号: HZ-3331R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

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 Rabbit Anti-Phospho-PFKFB3/PFK2 (Ser467)/FITC Conjugated antibody

FITC标记的磷酸化果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体

 

英文名称 Anti-Phospho-PFKFB3/PFK2 (Ser467)/FITC
中文名称 FITC标记的磷酸化果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体
别    名 6 phosphofructo 2 kinase/ fructose 2,6 bisphosphatase; 6 phosphofructo 2 kinase/fructose 2,6 biphosphatase 3; 6PF 2 K/Fru 2,6 P2ASE brain/placenta type isozyme; 6PF 2-K/Fru 2,6 P2ase 3; fructose 6 phosphate,2 kinase/fructose 2, 6 bisphosphatase; Inducible 6 phosphofructo 2 kinase/fructose 2,6 bisphosphatase; iPFK 2; IPFK2; PFK/FBPase 3; PFK-2; PFK2; Renal carcinoma antigen NY REN 56; uPFK 2; PFKFB3; F263_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 细胞生物  免疫学  信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human PFK2 around the phosphorylation site of Ser467
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]

Function:
Synthesis and degradation of fructose 2,6-bisphosphate.

Tissue Specificity:
Ubiquitous.

Similarity:
In the C-terminal section; belongs to the phosphoglycerate mutase family.

Database links:

Entrez Gene: 5209 Human

Entrez Gene: 170768 Mouse

Entrez Gene: 24640 Rat

Omim: 605319 Human

SwissProt: Q16875 Human

SwissProt: P25114 Rat

Unigene: 444304 Human

Unigene: 44844 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

由该基因编码的蛋白质属于双功能蛋白家族,参与了果糖-2,6-二磷酸的合成和降解,这是控制真核生物糖酵解的调节分子。编码的蛋白质具有6-磷酸果糖-2-激酶活性,催化果糖-2,6-二磷酸(F2,6BP)的合成,以及催化F2,6BP降解的果糖-2,6-双磷酸酶活性。这种蛋白质对细胞周期的进展和细胞凋亡的预防是必需的。它作为细胞周期蛋白依赖性激酶1的调节因子,将葡萄糖代谢与肿瘤细胞的增殖和存活联系起来。已经发现了几种编码不同亚型的交替剪接转录变体。[由RefSeq,APR 2016提供]