FITC标记的髓鞘转录因子1抗体-抗体-抗体-生物在线
FITC标记的髓鞘转录因子1抗体

FITC标记的髓鞘转录因子1抗体

商家询价

产品名称: FITC标记的髓鞘转录因子1抗体

英文名称: Anti-Myt1/FITC

产品编号: HZ-3505R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
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  • 邮箱 : www.shzbio.net

 Rabbit Anti-Myt1/FITC Conjugated antibody

 

FITC标记的髓鞘转录因子1抗体
英文名称 Anti-Myt1/FITC
中文名称 FITC标记的髓鞘转录因子1抗体
别    名 C20orf36; MTF1; Myelin transcription factor 1; Myelin transcription factor I; MyT1; MYT1_HUMAN; MyTI; PLPB1; Proteolipid protein-binding protein.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  神经生物学  信号转导  细胞凋亡  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 122kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Myt1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Myt1 is a zinc finger protein that is known to interact with the co-repressor Sin3B and also HDAC1 and HDAC2. The Myt1 family, including Myt1 and Myt1L, exemplifies a class of neural sequence specific transcription factors that actively recruit HDACs to selected genes during CNS development.

Function:
Binds to the promoter regions of proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendrogalia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription.

Subunit:
nteracts with STEAP3.

Subcellular Location:
Nucleus.

Tissue Specificity:
Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes.

Similarity:
Contains 7 C2HC-type zinc fingers.

Database links:

Entrez Gene: 4661 Human

Entrez Gene: 17932 Mouse

Omim: 600379 Human

SwissProt: Q01538 Human

SwissProt: Q8CFC2 Mouse

Unigene: 279562 Human

Unigene: 458718 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

 

MYT1是已知的与锌阻遏物Sn3b和HDAC1和HDAC2相互作用的锌指蛋白。MyT1家族,包括MYT1和MYT1L,例证了一类神经序列特异性转录因子,其在中枢神经系统发育过程中主动招募HDACs至所选择的基因。