FITC标记的神经突触素2抗体
产品名称: FITC标记的神经突触素2抗体
英文名称: Anti-Synapsin II/FITC
产品编号: HZ-3502R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-Synapsin II/FITC Conjugated antibody
FITC标记的神经突触素2抗体
英文名称 | Anti-Synapsin II/FITC |
中文名称 | FITC标记的神经突触素2抗体 |
别 名 | SYN 2; SYN II; SYN IIa; SYN IIb; SYN2; Synapsin 2; Synapsin II isoform IIa; Synapsin II isoform IIb; Synapsin2; SynapsinII; SYNII; SYNIIa; SYNIIb; SYN2_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 神经生物学 信号转导 转录调节因子 细胞表面分子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Sheep, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 63kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Synapsin II |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts. [provided by RefSeq, Jul 2008] Function: Neuronal phosphoprotein that coats synaptic vesicles,binds to the cytoskeleton, and is believed to function in theregulation of neurotransmitter release. Subunit: Interacts with CAPON. Subcellular Location: Cell junction, synapse. Tissue Specificity: Central and peripheral nervous systems. Post-translational modifications: Phosphorylation at Ser-10 dissociates synapsins from synapticvesicles. Similarity: Belongs to the synapsin family. Database links: Entrez Gene: 6854 Human Entrez Gene: 20965 Mouse Entrez Gene: 29179 Rat Omim: 600755 Human SwissProt: Q92777 Human SwissProt: Q64332 Mouse SwissProt: Q63537 Rat Unigene: 445503 Human Unigene: 506 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因是突触素基因家族的成员。突触蛋白编码神经元磷蛋白,其与突触小泡的细胞质表面相关。家族成员具有共同的蛋白质结构域,它们参与突触发生和神经递质释放的调节,提示在一些神经精神疾病中可能发挥作用。突触蛋白家族的成员编码一种神经元特异性磷蛋白,选择性地结合突触前神经末梢中的小突触囊泡。TIMP4基因位于该基因的内含子中,并在相反的方向上转录。该基因的突变可能与异常突触前功能和精神分裂症有关。该基因的选择性剪接导致两个转录本。[ RefSeq,JUL 2008 ]