FITC标记的神经突触素2抗体-抗体-抗体-生物在线
FITC标记的神经突触素2抗体

FITC标记的神经突触素2抗体

商家询价

产品名称: FITC标记的神经突触素2抗体

英文名称: Anti-Synapsin II/FITC

产品编号: HZ-3502R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

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 Rabbit Anti-Synapsin II/FITC Conjugated antibody

FITC标记的神经突触素2抗体

 

英文名称 Anti-Synapsin II/FITC
中文名称 FITC标记的神经突触素2抗体
别    名 SYN 2; SYN II; SYN IIa; SYN IIb; SYN2; Synapsin 2; Synapsin II isoform IIa; Synapsin II isoform IIb; Synapsin2; SynapsinII; SYNII; SYNIIa; SYNIIb; SYN2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  神经生物学  信号转导  转录调节因子  细胞表面分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Sheep, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Synapsin II
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts. [provided by RefSeq, Jul 2008]

Function:
Neuronal phosphoprotein that coats synaptic vesicles,binds to the cytoskeleton, and is believed to function in theregulation of neurotransmitter release.

Subunit:
Interacts with CAPON.

Subcellular Location:
Cell junction, synapse.

Tissue Specificity:
Central and peripheral nervous systems. 

Post-translational modifications:
Phosphorylation at Ser-10 dissociates synapsins from synapticvesicles.

Similarity:
Belongs to the synapsin family. 

Database links:

Entrez Gene: 6854 Human

Entrez Gene: 20965 Mouse

Entrez Gene: 29179 Rat

Omim: 600755 Human

SwissProt: Q92777 Human

SwissProt: Q64332 Mouse

SwissProt: Q63537 Rat

Unigene: 445503 Human

Unigene: 506 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

该基因是突触素基因家族的成员。突触蛋白编码神经元磷蛋白,其与突触小泡的细胞质表面相关。家族成员具有共同的蛋白质结构域,它们参与突触发生和神经递质释放的调节,提示在一些神经精神疾病中可能发挥作用。突触蛋白家族的成员编码一种神经元特异性磷蛋白,选择性地结合突触前神经末梢中的小突触囊泡。TIMP4基因位于该基因的内含子中,并在相反的方向上转录。该基因的突变可能与异常突触前功能和精神分裂症有关。该基因的选择性剪接导致两个转录本。[ RefSeq,JUL 2008 ]