FITC标记的类固醇受体激活蛋白2抗体
产品名称: FITC标记的类固醇受体激活蛋白2抗体
英文名称: Anti-KAT13C/FITC
产品编号: HZ-
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
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- 传真 : 021-60345367
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Rabbit Anti-KAT13C/FITC Conjugated antibody
FITC标记的类固醇受体激活蛋白2抗体
英文名称 | Anti-KAT13C/FITC |
中文名称 | FITC标记的类固醇受体激活蛋白2抗体 |
别 名 | NCOA2; KAT13C; glucocorticoid receptor interacting protein 1; GRIP 1; GRIP1; MED1; MGC138808; NCoA 2; nuclear receptor coactivator 2; Oncogene FGR; p160; SRC 2; src2; Steroid receptor coactivator 2; TIF 2; TIF2; Transcriptional intermediary factor 2; NCOA2_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 信号转导 细胞凋亡 转录调节因子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 159kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NCOA2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcriptional activity of the nuclear receptor with which they associate. One such coactivator is KAT13C / nuclear receptor coactivator 2 (NCOA2), also termed Glucocorticoid receptor-interacting protein 1 (GRIP1). Subcellular Location: Nucleus. Similarity: Belongs to the SRC/p160 nuclear receptor coactivator family. Contains 1 basic helix-loop-helix (bHLH) domain. Contains 1 PAS (PER-ARNT-SIM) domain. Database links: Entrez Gene: 10499 Human Omim: 601993 Human SwissProt: Q15596 Human Unigene: 446678 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
类固醇和甲状腺和视黄酸通过配体依赖性核受体超家族的细胞内受体转录因子调节复杂的基因表达活性。增加这些转录因子功能的复杂性是称为辅激活蛋白和辅阻遏蛋白的相关蛋白,正如它们的名字所暗示的,增强或抑制它们所关联的核受体的转录活性。一个这样的共激活子是KAT13C/核受体共激活子2(NCOA2),也称为糖皮质受体相互作用蛋白1(GRIP1)。