FITC标记的染色质结合蛋白Cbx8抗体-抗体-抗体-生物在线
FITC标记的染色质结合蛋白Cbx8抗体

FITC标记的染色质结合蛋白Cbx8抗体

商家询价

产品名称: FITC标记的染色质结合蛋白Cbx8抗体

英文名称: Anti-Cbx8/FITC

产品编号: HZ-3500R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

 Rabbit Anti-Cbx8/FITC Conjugated antibody

FITC标记的染色质结合蛋白Cbx8抗体

 

英文名称 Anti-Cbx8/FITC
中文名称 FITC标记的染色质结合蛋白Cbx8抗体
别    名 Chromobox protein homolog 8; HPC3; Pc3; Polycomb 3 homolog; RC1; Rectachrome 1; CBX8_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  免疫学  信号转导  干细胞  转录调节因子  结合蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cbx8
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Cbx8, also known as Pc3, is a member of the Polycomb gene family and is required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Cbx8 contains a chromodomain and is able to modify chromatin and histones.

Function:
Component of a Polycomb group (PcG) multiproteinPRC1-like complex, a complex class required to maintain thetranscriptionally repressive state of many genes, including Hoxgenes, throughout development. PcG PRC1 complex acts via chromatinremodeling and modification of histones; it mediatesmonoubiquitination of histone H2A 'Lys-119', rendering chromatinheritably changed in its expressibility.

Subunit:
Component of a PRC1-like complex. Interacts with RING1RNF2, PCGF1, PCGF2, PCGF3, BMI1, PCGF5 AND PCGF6. Interacts withMLLT3 and histone H3. Interacts with PHC2 (By similarity).

Subcellular Location:
Nucleus.

Similarity:
Contains 1 chromo domain.

Database links:

Entrez Gene: 506458 Cow

Entrez Gene: 57332 Human

Entrez Gene: 30951 Mouse

Entrez Gene: 303731 Rat

SwissProt: Q9HC52 Human

SwissProt: Q9QXV1 Mouse

Unigene: 387258 Human

Unigene: 99953 Mouse

Unigene: 43722 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

CBX8,又称PC3,是多梳基因家族的成员,在整个发育过程中,需要维持许多基因(包括Hox基因)的转录抑制状态。CBX8含有染色质,能够修饰染色质和组蛋白。