FITC标记的PE标记小鼠抗人CD5单克隆抗体
产品名称： FITC标记的PE标记小鼠抗人CD5单克隆抗体
英文名称： Anti-human CD5-PE/FITC
产品编号： HZ-30067M-PE-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： Flow-Cyt=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
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Rabbit Anti-human CD5-PE/FITC Conjugated antibody
FITC标记的PE标记小鼠抗人CD5单克隆抗体
| 英文名称 | Anti-human CD5-PE/FITC |
| 中文名称 | FITC标记的PE标记小鼠抗人CD5单克隆抗体 |
| 别 名 | T-cell surface glycoprotein CD5; Lymphocyte antigen 1; Ly-1; Lyt-1; CD5; CD5 antigen; CD 5; CD5 molecule; CD5 antigen (p56 62); CD5_HUMAN; LEU 1; LEU1; Ly12; LyA; Lymphocyte Antigen CD5; Lymphocyte antigen T1/Leu 1; Lymphocyte antigen T1/Leu-1; Lymphocyte glycoprotein T1/Leu1; OTTHUMP00000236973; p56 62; T1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 干细胞 细胞表面分子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | Flow-Cyt=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 55kDa |
| 性 状 | Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] Function: May act as a receptor in regulating T-cell proliferation. Subunit: Interacts with CD72/LYB-2. Interacts with PTPN6/SHP-1. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Post-translational modifications: Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1. Similarity: Contains 3 SRCR domains. Database links: Entrez Gene: 921 Human Omim: 153340 Human SwissProt: P06127 Human Unigene: 58685 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码调节补体介导的细胞裂解的细胞表面糖蛋白，参与淋巴细胞信号转导。这种蛋白质是补体膜攻击复合物的有力抑制剂，因此它在配合物的组装过程中结合补体C8和/或C9，从而抑制C9的多个复合体掺入复合物中，这是渗透压孔形成所必需的。该蛋白在T细胞活化过程中也起着信号转导通路的作用。该基因的突变导致CD59缺乏，这是一种导致溶血性贫血和血栓形成的疾病，并导致脑梗塞。多个交替剪接的转录变体，编码相同的蛋白质，已被鉴定为该基因。[ RefSeq，JUL 2008 ]