FITC标记的磷酸化星形胶质细胞PEA15抗体-抗体-抗体-生物在线
FITC标记的磷酸化星形胶质细胞PEA15抗体

FITC标记的磷酸化星形胶质细胞PEA15抗体

商家询价

产品名称: FITC标记的磷酸化星形胶质细胞PEA15抗体

英文名称: Anti-Phospho-PEA15 (Ser104)/FITC

产品编号: HZ-3328R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

上海沪震实业有限公司
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 Rabbit Anti-Phospho-PEA15 (Ser104)/FITC Conjugated antibody 

FITC标记的磷酸化星形胶质细胞PEA15抗体

 

英文名称 Anti-Phospho-PEA15 (Ser104)/FITC
中文名称 FITC标记的磷酸化星形胶质细胞PEA15抗体
别    名 PEA15(Phospho Ser104); PEA15 (Phospho-S104); p-PEA15 (Ser104); Astrocytic phosphoprotein PEA 15; Astrocytic phosphoprotein PEA15; HMAT 1; HMAT1; Homolog of mouse MAT 1 oncogene; Homolog of mouse MAT1 oncogene; HUMMAT 1H; HUMMAT1H; MAT 1; MAT 1H; MAT1; MAT1H; PEA 15; PEA-15; PEA15 protein; PED; Phosphoprotein enriched in astrocytes 15; Phosphoprotein enriched in astrocytes 15kD; Phosphoprotein enriched in diabetes.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 免疫学  神经生物学  细胞凋亡  转录调节因子  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 15kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human PEA15 around the phosphorylation site of Ser104
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
PED/PEA 15 (Phosphoprotein Enriched in Diabetes/Phosphoprotein Enriched in Astrocytes 15 kDa) is a widely expressed 15 kDa protein comprised of an N terminal region containing a canonical Death Effector Domain (DED) sequence and a nuclear export signal, and a C terminal region containing two serine phosphorylation sites. PED/PEA 15 has been implicated in the regulation of multiple cellular processes including apoptosis, integrin activation, and insulin sensitive glucose transport in insulin responsive cells. Phosphorylation of both serine 104 (a Protein Kinase C site) and serine 116 (a substrate of CaMKII and Akt) is required for PED/PEA 15 function.

Subunit:
Binds RPS6KA3, MAPK3 and MAPK1. Transient interaction with PLD1 and PLD2 (By similarity). Interacts with CASP8 and FADD.

Subcellular Location:
Cytoplasm. 

Tissue Specificity:
Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose-producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls.

Similarity:
Contains 1 DED (death effector) domain.

Database links:

Entrez Gene: 8682 Human

Entrez Gene: 18611 Mouse

Omim: 603434 Human

SwissProt: Q15121 Human

SwissProt: Q62048 Mouse

Unigene: 517216 Human

Unigene: 544 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

PED/PEA 15(富含糖尿病的星形胶质蛋白/富含星形胶质细胞的磷酸化蛋白15 kDa)是一种广泛表达的15 kDa蛋白,由包含典型死亡效应域(DE)序列和核输出信号的N末端区域和含有两个丝氨酸的C末端区域组成。磷酸化位点。PED/PEA 15参与了多种细胞过程的调节,包括细胞凋亡、整合素激活和胰岛素敏感细胞中的胰岛素敏感葡萄糖转运。丝氨酸104(蛋白激酶C位点)和丝氨酸116(CAMKII和AKT的底物)的磷酸化对于PED/PEA 15功能是必需的。