FITC标记的1号染色体开放阅读框84抗体
产品名称： FITC标记的1号染色体开放阅读框84抗体
英文名称： Anti-C1orf84 /FITC
产品编号： HZ-15077R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-C1orf84 /FITC Conjugated antibody
FITC标记的1号染色体开放阅读框84抗体
| 英文名称 | Anti-C1orf84 /FITC |
| 中文名称 | FITC标记的1号染色体开放阅读框84抗体 |
| 别 名 | Chromosome 1 open reading frame 84; Hypothetical protein LOC149469; Uncharacterized protein C1orf84; SZT2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 378kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C1orf84 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: SZT2 (seizure threshold 2 homolog (mouse)), also known as SZT2A or SZT2B, is a 3,432 amino acid peroxisomal protein that plays a role in resistance to oxidative stress. Predominantly expressed in the parietal and frontal cortex, as well as in dorsal root ganglia of the brain, SZT2 is implicated in superoxide dismutase activity and the neuroprotection in peroxisomes. Existing as four alternatively spliced isoforms, SZT2 is thought to enhance epileptogenesis and is encoded by a gene that maps to human chromosome 1p34.2. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Function: Involved in oxidative stress. May be involved in superoxide dismutase activity and in neuroprotective effect of peroxisomes, but has no direct dismutase activity when tested in yeast. May enhance epileptogenesis and confer low seizure threshold (By similarity). Subcellular Location: Peroxisome (By similarity). Tissue Specificity: Expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. Database links: UniProtKB/Swiss-Prot: Q5T011.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SZT2（惊厥阈值2同源物（小鼠）），也称为SZT2A或SZT2B，是一种3432个氨基酸的过氧异构体蛋白，在抗氧化应激中起作用。SZT2主要表达于大脑顶叶和额叶皮质以及背根神经节，与过氧化物酶体的超氧化物歧化酶活性和神经保护有关。SZT2作为四种可选择的剪接异构体存在，被认为可以增强癫痫的发生，并且由映射到人类染色体1p34.2的基因编码。人类1号染色体跨越2.6亿个碱基对，包含3000多个基因，包含近8%的人类基因组，并含有大量疾病相关基因，包括那些与家族性腺瘤性息肉病、Stickler综合征、帕金森病、Gaucher病有关的基因，精神分裂症和阿瑟小子综合征。