FITC标记的DNA酶1样蛋白1抗体
产品名称： FITC标记的DNA酶1样蛋白1抗体
英文名称： Anti-DNASE1L1/FITC
产品编号： HZ-12995R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-DNASE1L1/FITC Conjugated antibody
FITC标记的DNA酶1样蛋白1抗体
| 英文名称 | Anti-DNASE1L1/FITC |
| 中文名称 | FITC标记的DNA酶1样蛋白1抗体 |
| 别 名 | Deoxyribonuclease I-like 1; Deoxyribonuclease I like 1; Deoxyribonuclease-1-like 1; DNAS1L1; DNase I like 1; DNase I like muscle specific; DNase I lysosomal like; DNase I-like 1; DNase X; DNASE1L1; DNASEX; DNL1L; DNSL1_HUMAN; Muscle specific DNase I like; DNASEX; Muscle-specific DNase I-like; XIB. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 染色质和核信号 神经生物学 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DNASE1L1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: DNASE1L1 is a 302 amino acid protein that localizes to the endoplasmic reticulum and belongs to the deoxyribonuclease family. Expressed at high levels in cardiac and skeletal muscle and at lower levels in a variety of tissues throughout the body, DNASE1L1 exists as multiple alternatively spliced isoforms and is thought to function in a similar manner to DNase l, possibly mediating internucleosomal DNA degradation via catalytic cleavage events. The gene encoding DNASE1L1 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy. Subcellular Location: Endoplasmic reticulum. Tissue Specificity: Highest levels in skeletal and cardiac muscles. Detectable in all other tissues tested except brain. Similarity: Belongs to the DNase I family. Database links: UniProtKB/Swiss-Prot: P49184.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
DNASE1L1是一种定位于内质网的302氨基酸蛋白，属于脱氧核糖核酸酶家族。DNASE1L1在心肌和骨骼肌中高水平表达，在全身各种组织中低水平表达，作为多种可选择的剪接异构体存在，并且被认为以与DNase1相似的方式起作用，可能通过cata介导核糖体间DNA降解。裂解解理事件。编码DNASE1L1的基因定位于人类X染色体，其含有近1亿5300万个碱基对，并含有1000个以上基因。染色体Y与X染色体负责性别决定。有许多情况与性染色体的异常数目和组合有关，其中一些包括特纳综合征、色盲、血友病和杜氏肌营养不良。