Rabbit Anti-phospho-delta 1 Catenin (Tyr228)/FITC Conjugated antibody
|英文名称||Anti-phospho-delta 1 Catenin (Tyr228)/FITC|
|别 名||delta 1 Catenin (phospho Y228); p-delta 1 Catenin (phospho Y228); Cadherin associated Src substrate; Cadherin-associated Src substrate; CAS; Catenin (cadherin associated protein) delta 1; Catenin delta 1; Catenin delta-1; CTND1_HUMAN; CTNND 1; CTNND; CTNND1; KIAA0384; p120; P120 CAS; p120 catenin; P120 CTN; p120(cas); p120(ctn); P120CAS; P120CTN.|
|规格价格||100ul/2980元 购买 大包装/询价|
|说 明 书||100ul|
|研究领域||细胞生物 信号转导 干细胞 转录调节因子 细胞骨架|
|交叉反应||Human, Mouse, Rat,|
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||108kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthesised phosphopeptide derived from human delta 1 Catenin around the phosphorylation site of Tyr228|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010]
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway. May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
Cytoplasm. Nucleus. Cell membrane. Note=Interaction with GLIS2 promotes nuclear translocation. Detected at cell-cell contacts. NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation. NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
Expressed in vascular endothelium.
Phosphorylated by FER and other protein-tyrosine kinases. Phosphorylated at Ser-288 by PAK7/PAK5. Dephosphorylated by PTPRJ.
Belongs to the beta-catenin family.
Contains 10 ARM repeats.
Entrez Gene: 1500 Human
Entrez Gene: 12388 Mouse
Entrez Gene: 311163 Rat
Omim: 601045 Human
SwissProt: O60716 Human
SwissProt: P30999 Mouse
Unigene: 166011 Human
Unigene: 35738 Mouse
Unigene: 9435 Rat
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
这encodes基因家族成员which of the犰狳蛋白，在细胞粘附和功能之间的信号转导分子。多重选择性剪接的结果codons translation +和在许多不同isoforms被translated。not of the全长度的成绩单natures variants of the have been矛盾描述的程序***。通读转录本之间也neighboring exists和硫氧还蛋白基因上游的跨膜蛋白相关蛋白2基因（tmx2）。[提供]序列模式，2010年12月