FITC标记的22号染色体开放阅读框29抗体-抗体-抗体-生物在线
FITC标记的22号染色体开放阅读框29抗体

FITC标记的22号染色体开放阅读框29抗体

商家询价

产品名称: FITC标记的22号染色体开放阅读框29抗体

英文名称: Anti-C22orf29/FITC

产品编号: HZ-15135R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

 Rabbit Anti-C22orf29/FITC Conjugated antibody 

FITC标记的22号染色体开放阅读框29抗体

 

英文名称 Anti-C22orf29/FITC
中文名称 FITC标记的22号染色体开放阅读框29抗体
别    名 C22orf29; CV029_HUMAN; Uncharacterized protein C22orf29.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human C22orf29
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translo-acations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The C22orf29 gene product has been provisionally designated C22orf29 pending further characterization

Function:
Could induce apoptosis in a BH3 domain-dependent manner.The direct interaction network of Bcl-2 family members may play akey role in modulation BOP intrinsic apoptotic signaling activity.

Subunit:
Interacts (via BH3 domain) with VDAC1. Interacts withpro-survival Bcl-2 family members, BCL2, BCL2L1 isoform Bcl-X(L),MCL1, BCL2A1 and BCL2L2. Interacts with BAX and BAK. 

Subcellular Location:
Mitochondrion. 

Tissue Specificity:
Ubiquitously expressed. 

Database links:

Entrez Gene: 79680 Human

SwissProt: Q7L3V2 Human

Unigene: 105642 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

22号染色体含有500个以上的基因和4900万个碱基。作为第二个最小的人类染色体,22包含令人惊讶的各种有趣的基因。PelLAN McDeMID综合征,2型神经纤维瘤病和孤独症与22号染色体有关。在22号染色体上发现了一个精神分裂症易感位点,研究表明22q11缺失症状包括精神分裂症的高发病率。染色体9和22之间的转座作用可能导致费城染色体的形成和随后产生新的融合蛋白,Bcr-Abl,一种在几种类型的白血病中发现的有效的细胞增殖激活剂。c22Orf29基因产物已暂时指定为C22OF29,有待进一步鉴定。