FITC标记的离子转运相关蛋白SLC7A9抗体上海沪震实业有限公司

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产品名称: FITC标记的离子转运相关蛋白SLC7A9抗体
英文名称: Anti-SLC7A9/FITC
抗体货号: HZ-10085R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/9/13 10:49:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-SLC7A9/FITC Conjugated antibody

FITC标记的离子转运相关蛋白SLC7A9抗体

 

英文名称 Anti-SLC7A9/FITC
中文名称 FITC标记的离子转运相关蛋白SLC7A9抗体
别    名 B(0+) type amino acid transporter 1; BAT1; CSNU3; Glycoprotein associated amino acid transporter b0+AT1; Solute carrier family 7 (cationic amino acid transporter y+ system) member 9; BAT1_HUMAN; B(0,+)-type amino acid transporter 1; B(0,+)AT; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 免疫学  通道蛋白  交换蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Rabbit, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC7A9
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
SLC7A9 belongs to the amino acid-polyamine-organocation (APC) superfamily. It is a disulfide linked heterodimer with the amino acid transport protein SLC3A1. SLC7A9 is involved in the high affinity, sodium independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high affinity reabsorption of cystine in the kidney tubule. Defects in SLC7A9 are a cause of non type I cystinuria (CSNU). CSNU arises from impaired transport of cystine and dibasic amino acids through the epithelial cells of the renal tubule and gastrointestinal tract. Three types of cystinuria have been described: type I (fully recessive or silent); type II (high excretor); type III (moderate excretor). Defects in SLC7A9 are associated with type II and type III cystinuria. They also might account for some non classic type I cystinuria cases.

Function:
Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high-affinity reabsorption of cystine in the kidney tubule.

Subunit:
Disulfide-linked heterodimer with the amino acid transport protein SLC3A1.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Kidney, small intestine, liver and placenta.

Similarity:
Belongs to the amino acid-polyamine-organocation (APC) superfamily.

Database links:

Entrez Gene: 11136 Human

Entrez Gene: 30962 Mouse

Entrez Gene: 116726 Rat

Omim: 604144 Human

SwissProt: P82251 Human

SwissProt: Q3UQE3 Mouse

SwissProt: Q9QXA6 Mouse

SwissProt: P82252 Rat

SwissProt: Q4KM04 Rat

Unigene: 408567 Human

Unigene: 45874 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

SLC7A9属于氨基酸多胺有机化(APC)超家族。它是二硫键结合的异源二聚体,具有氨基酸转运蛋白SLC3A1。SLC7A9参与胱氨酸和中性和二元氨基酸的高亲和性、钠独立转运(系统b(0,+)-样活性)。认为胱氨酸在肾小管中具有高亲和性的再吸收。SLC7A9的缺陷是非I型胱氨酸尿症(CSNU)的原因之一。CSNU起因于胱氨酸和二元氨基酸通过肾小管和胃肠道上皮细胞的运输受损。已经描述了三种类型的胱氨酸尿:I型(完全隐性或无症状);II型(高排泄物);II型(中排泄物)。SLC7A9的缺陷与II型和III型胱氨酸尿症有关。他们也可以解释一些非经典型I型胱氨酸尿症。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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