FITC标记的离子转运相关蛋白SLC7A9抗体
产品名称： FITC标记的离子转运相关蛋白SLC7A9抗体
英文名称： Anti-SLC7A9/FITC
产品编号： HZ-10085R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-SLC7A9/FITC Conjugated antibody
FITC标记的离子转运相关蛋白SLC7A9抗体
| 英文名称 | Anti-SLC7A9/FITC |
| 中文名称 | FITC标记的离子转运相关蛋白SLC7A9抗体 |
| 别 名 | B(0+) type amino acid transporter 1; BAT1; CSNU3; Glycoprotein associated amino acid transporter b0+AT1; Solute carrier family 7 (cationic amino acid transporter y+ system) member 9; BAT1_HUMAN; B(0,+)-type amino acid transporter 1; B(0,+)AT; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 免疫学 通道蛋白 交换蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 53kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SLC7A9 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: SLC7A9 belongs to the amino acid-polyamine-organocation (APC) superfamily. It is a disulfide linked heterodimer with the amino acid transport protein SLC3A1. SLC7A9 is involved in the high affinity, sodium independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high affinity reabsorption of cystine in the kidney tubule. Defects in SLC7A9 are a cause of non type I cystinuria (CSNU). CSNU arises from impaired transport of cystine and dibasic amino acids through the epithelial cells of the renal tubule and gastrointestinal tract. Three types of cystinuria have been described: type I (fully recessive or silent); type II (high excretor); type III (moderate excretor). Defects in SLC7A9 are associated with type II and type III cystinuria. They also might account for some non classic type I cystinuria cases. Function: Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high-affinity reabsorption of cystine in the kidney tubule. Subunit: Disulfide-linked heterodimer with the amino acid transport protein SLC3A1. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Kidney, small intestine, liver and placenta. Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Database links: Entrez Gene: 11136 Human Entrez Gene: 30962 Mouse Entrez Gene: 116726 Rat Omim: 604144 Human SwissProt: P82251 Human SwissProt: Q3UQE3 Mouse SwissProt: Q9QXA6 Mouse SwissProt: P82252 Rat SwissProt: Q4KM04 Rat Unigene: 408567 Human Unigene: 45874 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SLC7A9属于氨基酸多胺有机化（APC）超家族。它是二硫键结合的异源二聚体，具有氨基酸转运蛋白SLC3A1。SLC7A9参与胱氨酸和中性和二元氨基酸的高亲和性、钠独立转运(系统b(0,+)-样活性)。认为胱氨酸在肾小管中具有高亲和性的再吸收。SLC7A9的缺陷是非I型胱氨酸尿症（CSNU）的原因之一。CSNU起因于胱氨酸和二元氨基酸通过肾小管和胃肠道上皮细胞的运输受损。已经描述了三种类型的胱氨酸尿：I型（完全隐性或无症状）；II型（高排泄物）；II型（中排泄物）。SLC7A9的缺陷与II型和III型胱氨酸尿症有关。他们也可以解释一些非经典型I型胱氨酸尿症。