Rabbit Anti-CD93/FITC Conjugated antibody
|别 名||C1qrp; Complement component C1q receptor; C1q/MBL/SPA receptor; C1qR(p); C1qr1; C1qRp; CD93 antigen; CD93 molecule; CDw93; Complement component 1 q subcomponent receptor 1; Complement component C1q receptor; dJ737E23.1; ECSM3; Ly68; Matrix remodeling associated protein 4; MXRA4.|
|规格价格||100ul/2980元 购买 大包装/询价|
|说 明 书||100ul|
|研究领域||免疫学 细胞粘附分子 细胞表面分子 糖蛋白|
|交叉反应||Human, Mouse, Rat, Dog,|
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||70kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthetic peptide derived from human CD93|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq, Jul 2008].
Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.
Interacts with HCV core protein. Interacts with C1QBP; the association may represent a cell surface C1q receptor.
Membrane; Single-pass type I membrane protein.
Highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. Not expressed in cells of lymphoid origin.
N- and O-glycosylated.
Contains 1 C-type lectin domain.
Contains 5 EGF-like domains.
Entrez Gene: 22918 Human
Entrez Gene: 17064 Mouse
Entrez Gene: 84398 Rat
Omim: 120577 Human
SwissProt: Q9NPY3 Human
SwissProt: O89103 Mouse
SwissProt: Q9ET61 Rat
Unigene: 97199 Human
Unigene: 681 Mouse
Unigene: 162695 Rat
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
该基因编码的蛋白是细胞表面糖蛋白和I型膜蛋白，最初被鉴定为髓系细胞特异性标记。编码蛋白曾经被认为是C1q的受体，但现在被认为与细胞间粘附和凋亡细胞的清除有关。已发现这种蛋白质的细胞质内尾部与moesin相互作用，已知moesin在将跨膜蛋白连接至细胞骨架和细胞骨架的重建中发挥作用。[ RefSeq，JUL 2008 ]提供。