FITC标记的DLST蛋白抗体
产品名称： FITC标记的DLST蛋白抗体
英文名称： Anti-DLST/FITC
产品编号： HZ-13008R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
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- 邮编 : 200612
- 所在区域 : 上海
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Rabbit Anti-DLST/FITC Conjugated antibody
FITC标记的DLST蛋白抗体
| 英文名称 | Anti-DLST/FITC |
| 中文名称 | FITC标记的DLST蛋白抗体 |
| 别 名 | 2-oxoglutarate dehydrogenase complex component E2; Dihydrolipoamide S succinyltransferase (E2 component of 2 oxo glutarate complex); Dihydrolipoamide S succinyltransferase; Dihydrolipoamide succinyltransferase component of 2 oxoglutarate dehydrogenase complex; Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Dihydrolipoyllysine residue succinyltransferase component of 2 oxoglutarate dehydrogenase complex; Dihydrolipoyllysine residue succinyltransferase component of 2 oxoglutarate dehydrogenase complex mitochondrial; Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Dlst; DLTS; E2; E2K; mitochondrial; ODO2_HUMAN; OGDC-E2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 淋巴细胞 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DLST |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. The complex contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). DLST (dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial), also known as DLTS or 2-oxoglutarate dehydrogenase complex component E2, is a 453 amino acid protein belonging to the 2-oxoacid dehydrogenase family. DLST covalently binds one lipoyl cofactor and participates in L-lysine degradation via the saccharopine pathway. Localized to the mitochondrion, DLST forms a 24-polypeptide structural core with octahedral symmetry. The gene encoding DLST maps to human chromosome 14q24.3 and mouse chromosome 12 D2. Function: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Subunit: Forms a 24-polypeptide structural core with octahedral symmetry. Subcellular Location: Mitochondrion. Similarity: Belongs to the 2-oxoacid dehydrogenase family. Contains 1 lipoyl-binding domain. Database links: Entrez Gene: 1743 Human Entrez Gene: 78920 Mouse Entrez Gene: 299201 Rat Omim: 126063 Human SwissProt: P36957 Human SwissProt: Q9D2G2 Mouse SwissProt: Q01205 Rat Unigene: 525459 Human Unigene: 296221 Mouse Unigene: 99702 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
2-酮戊二酸脱氢酶复合物催化2-羰基戊二酸转化为琥珀酰辅酶A和CO2。该复合物包含三个酶组分的多个拷贝：2-氧戊二酸脱氢酶（E1）、二氢脂酰胺琥珀酰转移酶（E2）和脂酰胺脱氢酶（E3）。DLST(2-氧戊二酸脱氢酶复合物的二氢脂酰赖氨酸残基琥珀酰转移酶组分，线粒体)又称DLTS或2-氧戊二酸脱氢酶复合物E2，是属于2-氧乙酸脱氢酶家族的453个氨基酸。DLST共价结合一个脂酰辅酶，参与糖赖氨酸途径的L-赖氨酸降解。DLST定位于线粒体，形成具有八面体对称性的24多肽结构核心。编码DLST的基因定位于人类染色体14q24.3和小鼠染色体12 D2。