FITC标记的烯酰辅酶A水合酶含结构域蛋白2抗体上海沪震实业有限公司

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产品名称: FITC标记的烯酰辅酶A水合酶含结构域蛋白2抗体
英文名称: Anti-ECHDC2/FITC
抗体货号: HZ-13049R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/9/14 9:10:00
详细资料:  实验方法技术资料
浏览人数:12
诚信指数:1084点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
地址:
上海市杨浦区密云路1018号复旦科技园808室
邮编:
200612
电话:
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传真:
021-31320307
联系人:
陈先生
所在区域:
上海·中国-上海
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产品详细描述

 Rabbit Anti-ECHDC2/FITC Conjugated antibody

FITC标记的烯酰辅酶A水合酶含结构域蛋白2抗体

 

英文名称 Anti-ECHDC2/FITC
中文名称 FITC标记的烯酰辅酶A水合酶含结构域蛋白2抗体
别    名 1300017C12Rik; 2610009M20Rik; D4Ertd765e; Enoyl Coenzyme A hydratase domain containing 2; FLJ10948; Enoyl-CoA hydratase domain-containing protein 2; RGD1308525; RP23-379K6.3; ECHD2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  神经生物学  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Zebrafish, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ECHDC2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
ECHDC2 is a 292 amino acid mitochondrial protein that exists as two isoforms which are produced by alternative splicing events. The gene encoding ECHDC2 maps to chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 encodes a large number of disease-associated proteins, including Lamin A which, when expressed abnormally, can build up in the nucleus and cause nuclear blebs, a characteristic of the rare aging disease Hutchinson-Gilford progeria. Additionally, genes that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinsons Disease, Gaucher disease, schizophrenia and Usher syndrome are all located on chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Function:
ECHDC2 belongs to the enoyl-CoA hydratase/isomerase family. There are two named isforms.

Subcellular Location:
Mitochondrion (Potential).

Similarity:
Belongs to the enoyl-CoA hydratase/isomerase family.

Database links:
UniProtKB/Swiss-Prot: Q86YB7.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

ECHDC2是一种292氨基酸的线粒体蛋白,存在于两种异构体中,这两种亚型是由选择性剪接事件产生的。编码ECHDC2的基因定位于1号染色体,跨越2.6亿个碱基对,包含3000多个基因,占人类基因组的近8%。染色体1编码大量疾病相关蛋白,包括层粘连蛋白A,当其表达异常时,层粘连蛋白A可在细胞核内积聚并引起核小泡,这是罕见的老化病Hutchinson-Gilford progeria的特征。此外,与家族性腺瘤性息肉病、Stickler综合征、帕金森病、Gaucher病、精神分裂症和Usher综合征相关的基因都位于第1染色体上。染色体1异常存在于各种癌症中,包括头颈癌、恶性黑色素瘤和多发性骨髓瘤。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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