Rabbit Anti-C2orf71/FITC Conjugated antibody
|别 名||Chromosome 2 open reading frame 71; Uncharacterized protein C2orf71; CB071_HUMAN.|
|规格价格||100ul/2980元 购买 大包装/询价|
|说 明 书||100ul|
|研究领域||细胞生物 免疫学 神经生物学|
|交叉反应||Human, Rat, Dog, Cow, Sheep,|
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||140kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthetic peptide derived from human C2orf71|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
The protein encoded by this gene is highly expressed in photoreceptors and may associate with the primary cilium of the outer segment. The encoded protein appears to undergo post-translational lipid modification. Nonsense and missense variants of this gene appear to cause a recessive form of retinitis pigmentosa. [provided by RefSeq, Jun 2010]
May play an important role in the development of normalvision.
Cell projection, cilium, photoreceptor outersegment.
Specifically expressed in retina.
Defects in C2orf71 are the cause of retinitis pigmentosatype 54 (RP54) [MIM:613428]. A retinal dystrophy belonging to thegroup of pigmentary retinopathies. RP is characterized by retinalpigment deposits visible on fundus examination and primary loss ofrod photoreceptor cells followed by secondary loss of conephotoreceptors. Patients typically have night vision blindness andloss of midperipheral visual field. As their condition progresses,they lose their far peripheral visual field and eventually centralvision as well.
Entrez Gene: 388939 Human
Omim: 613425 Human
SwissProt: A6NGG8 Human
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
该基因编码的蛋白质在光感受器中高度表达，并可能与外段的原生纤毛结合。编码的蛋白质似乎经历翻译后脂质修饰。这种基因的无义和错义变异会导致视网膜色素变性的隐性形式。[ RefSeq 2010军提供]