FITC标记的磷酸化真核翻译延长因子2抗体上海沪震实业有限公司

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产品名称: FITC标记的磷酸化真核翻译延长因子2抗体
英文名称: Anti-Phospho-EEF2 (Thr56 + Thr58)/FITC
抗体货号: HZ-13057R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/9/14 9:42:00
详细资料:  实验方法技术资料
浏览人数:4
诚信指数:932点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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上海·中国-上海
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产品详细描述

 Rabbit Anti-Phospho-EEF2 (Thr56 + Thr58)/FITC Conjugated antibody

FITC标记的***酸化真核翻译延长因子2抗体

 

英文名称 Anti-Phospho-EEF2 (Thr56 + Thr58)/FITC
中文名称 FITC标记的***酸化真核翻译延长因子2抗体
别    名 EEF2 (phospho T56 + T58); p-EEF2 (phospho T56 + T58); EEF 2; Eef2; EF-2; EF2; EF2_HUMAN; Elongation factor 2; Eukaryotic translation elongation factor 2; Polypeptidyl tRNA translocase.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 ***酸化抗体 
研究领域 肿瘤  细胞生物  信号转导  细胞凋亡  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 95kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human EEF2 around the phosphorylation site of Thr56+Thr58
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
EEF2 is a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation.

Function:
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

Subunit:
Component of the mRNA surveillance SURF complex, at leastcomposed of ERF1, ERF3 (ERF3A or ERF3B), EEF2, UPF1/RENT1, SMG1,SMG8 and SMG9.

Subcellular Location:
Cytoplasm.

Post-translational modifications:
Phosphorylation by EF-2 kinase completely inactivates EF-2. Diphthamide is 2-[3-carboxyamido-3-(trimethyl-ammonio)propyl]histidine. Diphthamide can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A, thus arresting protein synthesis. ISGylated.

Similarity:
Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.

Database links:
UniProtKB/Swiss-Prot: P13639.4

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

EEF2是GTP结合翻译延伸因子家族的成员。这种蛋白质是蛋白质合成的一个重要因素。它促进了从A位点到核糖体的P位点的新生蛋白链的GTP相关易位。此蛋白完全被EF-2激酶***酸化失活。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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