FITC标记的延伸因子EF-1 γ抗体
产品名称: FITC标记的延伸因子EF-1 γ抗体
英文名称: Anti-EEF1G/FITC
产品编号: HZ-13056R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-EEF1G/FITC Conjugated antibody
FITC标记的延伸因子EF-1 γ抗体
英文名称 | Anti-EEF1G/FITC |
中文名称 | FITC标记的延伸因子EF-1 γ抗体 |
别 名 | 2610301D06Rik; AA407312; eEF 1B gamma; EEF 1G; eEF-1B gamma; EEF1G; EF 1 gamma; EF 1G; EF-1-gamma; EF1 gamma; EF1G; EF1G_HUMAN; Elongation factor 1 gamma; Elongation factor 1-gamma; Eukaryotic translation elongation factor 1 gamma; GIG 35; GIG35; MGC103354; MGC114210; MGC144723; MGC144724; MGC94929; Pancreatic tumor related protein; PRO1608; Translation elongation factor eEF 1 gamma chain. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 转录调节因子 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 50kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human EEF1G |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: EF-1 (elongation factor-1) is a multi-protein complex that is responsible for the delivery of aminoacyl-tRNAs to the ribosome. EF-1 gamma (elongation factor 1-gamma), also known as EEF1G or GIG35, is a 437 amino acid subunit of the EF-1 complex. Expressed in stomach, pancreas, brain, lung, kidney, intestine, liver and spleen, EF-1 gamma contains an N-terminal glutathione transferase domain which is thought to be involved in anchoring the complex to various cellular components. Additionally, EF-1 gamma may play a key role in the assembly of multiprotein complexes containing aminoacyl-tRNA synthetases. Increased expression of EF-1 gamma is associated with pancreatic cancer, suggesting a possible role for EF-1 gamma in the oncogenic transformation process. Function: Probably plays a role in anchoring the complex to other cellular components. Subunit: EF-1 is composed of four subunits: alpha, beta, delta, and gamma. Tissue Specificity: Highly expressed in pancreatic tumor tissue and to a lesser extent in normal kidney, intestine, pancreas, stomach, lung, brain, spleen and liver. Similarity: Contains 1 EF-1-gamma C-terminal domain. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain. Database links: UniProtKB/Swiss-Prot: P26641.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
EF-1(延伸因子-1)是一种多蛋白复合物,负责将氨基酰基TrNa递送到核糖体。EF-1γ(延伸因子1-Gamma),也称为EEF1G或GY35,是EF-1复合物的437个氨基酸亚基。EF-1γ表达于胃、胰腺、脑、肺、肾、肠、肝和脾脏,含有N端谷胱甘肽转移酶结构域,被认为参与将复合物锚定到各种细胞成分。此外,EF-1γ可能在含有氨酰基-tRNA合成酶的多蛋白复合物的组装中起关键作用。EF-1γ表达增加与胰腺癌有关,提示EF-1γ在致癌转化过程中可能起作用。