FITC标记的内质网定位蛋白ERGI3抗体
产品名称： FITC标记的内质网定位蛋白ERGI3抗体
英文名称： Anti-ERGI3/FITC
产品编号： HZ-13103R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
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- 邮编 : 200612
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Rabbit Anti-ERGI3/FITC Conjugated antibody
FITC标记的内质网定位蛋白ERGI3抗体
| 英文名称 | Anti-ERGI3/FITC |
| 中文名称 | FITC标记的内质网定位蛋白ERGI3抗体 |
| 别 名 | 2310015B14Rik; AV318804; C20orf47; CGI 54; D2Ucla1; dJ477O4.2; DKFZp547A2190; Endoplasmic reticulum Golgi intermediate compartment protein 3; endoplasmic reticulum localized protein ERp43; Endoplasmic reticulum-Golgi intermediate compartment protein 3; ERGI3_HUMAN; ERGIC and golgi 3; ergic3; ERV46; NY BR 84; PRO0989; RP23-220D12.2; RP3-477O4.1; SDBCAG84; serologically defined breast cancer antigen 84; Serologically defined breast cancer antigen NY BR 84; Serologically defined breast cancer antigen NY-BR-84. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 转运蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 43kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ERGI3/ERGIC-3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Cycling proteins play important roles in the organization and function of the early secretory pathway by participating in membrane traffic and selective transport of cargo between the endoplasmic reticulum (ER), the intermediate compartment (ERGIC), and the Golgi. A family of membrane bound, ubiquitous proteins involved in the selective transport of newly synthesized glycoproteins from the ER to the ERGIC include VIP36, ERGIC-53, ERGIC-1, ERGIC-2 and ERGIC-3. ERGIC-1, also designated ERGIC32, is thought to modulate the activity of a complex formed by ERGIC-2, also designated Erv41, and ERGIC-3, also designated Erv46. ERGIC-2 and ERGIC-3 are both mammalian homologs of yeast proteins abundant in COPII-coated vesicles and localize to the Cis-face of the Golgi apparatus. Function: Possible role in transport between endoplasmic reticulum and Golgi. Subunit: Interacts with ERGIC1/ERGIC32. Subcellular Location: Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus > cis-Golgi network membrane. Endoplasmic reticulum membrane. Cycles between the endoplasmic reticulum and the Golgi. Similarity: Belongs to the ERGIC family. Database links: Entrez Gene: 51614 Human Entrez Gene: 66366 Mouse Entrez Gene: 296306 Rat SwissProt: Q9Y282 Human SwissProt: Q9CQE7 Mouse Unigene: 472558 Human Unigene: 141276 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
循环蛋白通过参与内质网（ER）、中间隔室（ERGIC）和高尔基体之间的膜运输和货物的选择性运输，在早期分泌途径的组织和功能中发挥重要作用。参与新合成的糖蛋白从ER到ERGIC的选择性转运的膜结合蛋白家族包括VIP36、ERGIC-53、ERGIC-1、ERGIC-2和ERGIC-3。ERGIC-1，也称为ERGIC32，被认为调节由ERGIC-2，也称为Erv41，和ERGIC-3，也称为Erv46形成的复合物的活性。ERGIC-2和ERGIC-3是富含COPII包被小泡的酵母蛋白的哺乳动物同源物，定位于高尔基体的顺面。