FITC标记的乙醇胺激酶2抗体
产品名称: FITC标记的乙醇胺激酶2抗体
英文名称: Anti-ETNK2/FITC
产品编号: HZ-13112R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-ETNK2/FITC Conjugated antibody
FITC标记的乙醇胺激酶2抗体
英文名称 | Anti-ETNK2/FITC |
中文名称 | FITC标记的乙醇胺激酶2抗体 |
别 名 | 4933417N20Rik; AI197444; EC 2.7.1.82; EKI 2; EKI2; EKI2_HUMAN; Ethanolamine kinase 2; Ethanolamine kinase like protein; Ethanolamine kinase-like protein; ETNK 2; ETNK2; FLJ10761; HMFT1716; RP11 74C13.2; Tuc1. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 信号转导 新陈代谢 跨膜蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Pig, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 45kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ETNK2/Ethanolamine kinase 2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Ethanolamine kinase 2, also known as EKI2, ETNK2 or HMFT1716, is a 386 amino acid protein that belongs to the choline/ethanolamine kinase family. Via the cytidine diphosphate (CDP) ethanolamine pathway, Ethanolamine kinase 2 catalyses the initial step of phosphatidylethanolamine (PtdEtn) biosynthesis. Ethanolamine kinase 2 is expressed in kidney, liver, testis, ovary and prostate, and is highly specific for ethanolamine phosphorylation. Upregulated during testis development, Ethanolamine kinase 2 may play an essential role in regulating placental hemostasis. Existing as three alternatively spliced isoforms, the gene encoding Ethanolamine kinase 2 maps to human and mouse chromosome 1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Function: Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity. Subcellular Location: Belongs to the choline/ethanolamine kinase family. Tissue Specificity: Expressed in kidney, liver, ovary, testis and prostate. Similarity: Belongs to the choline/ethanolamine kinase family. Database links: Entrez Gene: 55224 Human Entrez Gene: 214253 Mouse Entrez Gene: 100622861 Pig Entrez Gene: 360843 Rat Omim: 609859 Human SwissProt: Q9NVF9 Human SwissProt: A7MCT6 Mouse SwissProt: D3ZRW8 Rat Unigene: 497469 Human Unigene: 52111 Mouse Unigene: 65516 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
乙醇胺激酶2,又称EKI2、ETNK2或HMFT1716,是属于胆碱/乙醇胺激酶家族的386种氨基酸蛋白。通过胞苷二磷酸(CDP)乙醇胺途径,乙醇胺激酶2催化磷脂酰乙醇胺(PtdEtn)生物合成的初始步骤。乙醇胺激酶2在肾脏、肝脏、睾丸、卵巢和前列腺中表达,对乙醇胺磷酸化高度特异。在睾丸发育过程中上调,乙醇胺激酶在调节胎盘止血中起着至关重要的作用。作为三个交替剪接的亚型存在,编码乙醇胺激酶2的基因映射到人和小鼠染色体1。人类1号染色体跨越2.6亿个碱基对,包含3000多个基因,包含近8%的人类基因组,并含有大量疾病相关基因,包括那些与家族性腺瘤性息肉病、Stickler综合征、帕金森病、Gaucher病有关的基因,精神分裂症和阿瑟小子综合征。