FITC标记的粘蛋白13抗体上海沪震实业有限公司

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产品名称: FITC标记的粘蛋白13抗体
英文名称: Anti-MUC13/FITC
抗体货号: HZ-10074R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/9/14 10:27:00
详细资料:  实验方法技术资料
浏览人数:20
诚信指数:1084点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-MUC13/FITC Conjugated antibody

FITC标记的粘蛋白13抗体

 

英文名称 Anti-MUC13/FITC
中文名称 FITC标记的粘蛋白13抗体
别    名 MUC13 Down regulated in colon cancer 1; DRCC1; MUC 13; MUC-13; Mucin 13, cell surface associated; RECC; UNQ6194; MUC13_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Horse, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MUC13
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
MUC13 is a mucin. These are secreted or transmembrane glycoproteins that are expressed mainly in the digestive tract and on epithelial surfaces. MUC13 is upregulated in gastric cancer. Mucins have also been implicated in inflammatory bowel diseases.

Function:
Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.

Subunit:
Homodimer of beta subunits.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein (Potential). Secreted. Note=Also exists as a soluble form.

Tissue Specificity:
Highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach.

Post-translational modifications:
Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homo-oligomerization into dimers is dependent on intrachain disulfide bonds.
Highly N-glycosylated.

Similarity:
Contains 3 EGF-like domains.
Contains 1 SEA domain.

Database links:

Entrez Gene: 56667 Human

Omim: 612181 Human

SwissProt: Q9H3R2 Human

Unigene: 5940 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

MUC13是粘蛋白。这些是分泌或跨膜糖蛋白,主要在消化道和上皮表面表达。MUC13在胃癌中表达上调。粘蛋白也参与了炎症性肠病。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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