FITC标记的FAHD1蛋白抗体上海沪震实业有限公司

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产品名称: FITC标记的FAHD1蛋白抗体
英文名称: Anti-FAHD1/FITC
抗体货号: HZ-13132R-FITC
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/9/14 10:52:00
详细资料:  实验方法技术资料
浏览人数:4
诚信指数:932点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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邮编:
200612
电话:
021-60345367
传真:
021-31320307
联系人:
陈先生
所在区域:
上海·中国-上海
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产品详细描述

 Rabbit Anti-FAHD1/FITC Conjugated antibody

 

FITC标记的FAHD1蛋白抗体
英文名称 Anti-FAHD1/FITC
中文名称 FITC标记的FAHD1蛋白抗体
别    名 Acylpyruvase FAHD1; C16orf36; Chromosome 16 open reading frame 36; DKFZP566J2046; FAHD1; FAHD1_HUMAN; Fumarylacetoacetate hydrolase domain containing protein 1; Fumarylacetoacetate hydrolase domain-containing protein 1; MGC74876; mitochondrial; YISK like; YISK like/RJD15; YisK-like protein; YISKL.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  神经生物学  线粒体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FAHD1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
FAHD1 is a 224 amino acid protein belonging to the FAH family. Present as a homodimer, FAHD1 is thought to have hydrolase activity and uses magnesium and calcium as cofactors. The gene that encodes FAHD1 maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, making up nearly 3% of human cellular DNA. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

Function:
Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro.

Subunit:
Homodimer.

Subcellular Location:
Mitochondrion. Cytoplasm, cytosol.

Tissue Specificity:
Ubiquitous (at protein level).

Similarity:
Belongs to the FAH family.

Database links:
UniProtKB/Swiss-Prot: Q6P587.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application
   
   

 

FAHD1是属于FAH家族的224个氨基酸。目前,作为同源二聚体,FAHD1被认为具有水解酶活性,并使用镁和钙作为辅因子。编码FAHD1的基因定位于人类16号染色体,该染色体在大约9000万碱基对中编码900多个基因,占人类细胞DNA的近3%。GAN基因位于16号染色体上,随着突变,可能导致巨大的轴突神经病变,一种神经系统紊乱,特征是随着生长而增加功能障碍。罕见的Rubinstein-Taybi综合征也与染色体16有关,尽管是通过CREBBP基因编码的关键CREB结合蛋白。Rubinstein Taybi的症状包括精神发育迟滞和肿瘤生长和白细胞肿瘤的易感性。Crohn病是通过NOD2基因与16号染色体相关的胃肠道炎症状态。系统性红斑狼疮和许多其它与染色体16的着丝粒周区相关的自身免疫性疾病导致SLC5A11被鉴定为潜在的自身免疫调节剂。

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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