Rabbit Anti-Fibulin 7/FITC Conjugated antibody
|别 名||FBLN7; FBLN7_HUMAN; FIBL-7; Fibl7; Fibulin-7; TM14.|
|规格价格||100ul/2980元 购买 大包装/询价|
|说 明 书||100ul|
|研究领域||细胞生物 发育生物学 细胞粘附分子 细胞外基质|
|交叉反应||Human, Mouse, Rat, Pig, Horse,|
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||45kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthetic peptide derived from human Fibulin 7|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
Fibulin-7 is a 439 amino acid extracellular matrix protein that belongs to the Fibulin family. Containing two EGF-like domains and one sushi (CCP/SCR) domain, Fibulin-7 exists as four alternatively spliced isoforms. Fibulin-7 is considered an adhesion protein that interacts with extracellular matrix molecules in developing teeth, and may be involved in differentiation and maintenance of odontoblasts as well as in dentin formation. Fibulin-7 is post-translationally glycosylated with N-linked oligosaccharides and interacts with heparin, fibronectin, fibulin-1 and DSP (dentin sialophosphoprotein). Fibulin-7 is encoded by a gene located on human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome.
An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as in dentin formation.
Secreted, extracellular space, extracellular matrix.
Belongs to the fibulin family.
Contains 2 EGF-like domains.
Contains 1 Sushi (CCP/SCR) domain.
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FiBurin 7是属于Fibulin家族的439氨基酸胞外基质蛋白。含有两个表皮生长因子样结构域和一个寿司（CCP/SCR）结构域，FiBurin 7作为四个交替剪接的亚型存在。纤维蛋白-7被认为是一种粘附蛋白，在发育中的牙齿中与细胞外基质分子相互作用，并可能参与成牙本质细胞的分化和维持以及牙本质的形成。纤维蛋白-7被N-连接的低聚糖翻译后糖基化，并与肝素、纤维连接蛋白、纤维蛋白-1和DSP(牙本质涎***蛋白)相互作用。纤维蛋白-7由位于人类染色体2上的基因编码，该基因由2.37亿个碱基组成，编码1400多个基因，约占人类基因组的8％。