FITC标记的泛素样核糖体蛋白S30/MNSF-β抗体
产品名称: FITC标记的泛素样核糖体蛋白S30/MNSF-β抗体
英文名称: Anti-FAU/FITC
产品编号: HZ-13148R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
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Rabbit Anti-FAU/FITC Conjugated antibody
FITC标记的泛素样核糖体蛋白S30/MNSF-β抗体
英文名称 | Anti-FAU/FITC |
中文名称 | FITC标记的泛素样核糖体蛋白S30/MNSF-β抗体 |
别 名 | 40S ribosomal protein S30; asr1; FAU; FAU encoded ubiquitin like protein; FAU1; FBR MuSV associated ubiquitously expressed; Finkel Biskis Reilly murine sarcoma virus (FBR MuSV) ubiquitously expressed (fox derived); Finkel Biskis Reilly murine sarcoma virus (FBR MuSV) ubiquitously expressed; Finkel Biskis Reilly murine sarcoma virus ubiquitously expressed; FLJ22986; Fub1; Fubi; MNSFbeta; Monoclonal nonspecific suppressor factor beta; Ribosomal protein S30; RPS30; S30; UBIM_HUMAN; Ubiquitin like protein fubi and ribosomal protein S30; Ubiquitin like protein fubi; Ubiquitin like S30 fusion protein; Ubiquitin-like protein FUBI. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 表观遗传学 泛素 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 8kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FAU/MNSF-beta |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. A wide range of enzymes facilitate in the proteolytic Ub pathway, including monoclonal nonspecific suppressor factor-beta (MNSF-beta), a subunit of MNSF, which is a lymphokine product of a murine T cell hybrid-oma that restricts the production of LPS-induced immunoglobulin secreting cells in an antigen-nonspecific manner. MNSF-beta is a ubiquitin-like fusion protein consisting of the ribosomal protein S30 and a protein that shares 36% sequence identity with ubiquitin. This ubiquitin-like segment (Ubi-L) can be cleaved from MNSF-beta in the cytosol. Similarity: Belongs to the ubiquitin family. Database links: Entrez Gene: 2197 Human Omim: 134690 Human SwissProt: P35544 Human SwissProt: P62861 Human Unigene: 387208 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
的泛素(Ub)途径酶的步骤,包括三个连续的conjugation UB UB和促进大学substrates特定蛋白样分子。第一步,需要激活的ATP依赖性的C -端的泛素和泛素链组件由多个泛素激活酶E1的组件。然后结合的泛素链是在泛素- conjugating酶(E2)的泛素E2生成中间物。的泛素连接酶(E3)的catalyzes然后转移到泛素E2蛋白从适当的基板。广泛的蛋白水解泛素途径酶的便利,包括nonspecific单克隆抗体抑制因子-β(MNSFβ亚基(MNSF),这是一个产品,lymphokine小鼠T细胞杂交restricts OMA是生产的免疫球蛋白分泌细胞在LPS诱导的蚂蚁nonspecific抗原-的方式。Mnsfβ是一个泛素样蛋白组成的融合蛋白的核糖体蛋白S30和36 %的身份与这股泛素基因序列。这种泛素样部分(1 L)可以从cleaved-caspase-3 MNSFβ的cytosol。