FITC标记的慢性粒细胞白血病33抗体上海沪震实业有限公司

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产品名称: FITC标记的慢性粒细胞白血病33抗体
英文名称: Anti-FARSLA/CML33/FITC
抗体货号: HZ-
产品规格: 100ul
级    别: 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/9/14 11:25:00
详细资料:  实验方法技术资料
浏览人数:28
诚信指数:1084点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Rabbit Anti-FARSLA/CML33/FITC Conjugated antibody 

FITC标记的慢性粒细胞白血病33抗体

 

英文名称 Anti-FARSLA/CML33/FITC
中文名称 FITC标记的慢性粒细胞白血病33抗体
别    名 CML 33; CML33; FARS; FARSA; FARSL; FRSA; PheHA; Phenylalanine tRNA ligase 1 alpha cytoplasmic; Phenylalanine tRNA ligase alpha chain; Phenylalanine tRNA synthetase alpha subunit; Phenylalanine tRNA synthetase like alpha subunit; Phenylalanyl tRNA synthetase alpha chain; Phenylalanyl tRNA synthetase alpha subunit; Phenylalanyl tRNA synthetase like alpha subunit; PheRS.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FARSLA/CML33
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Aminoacyl-tRNA synthetases consist of a family of enzymes that catalyze the specific aminoacylation of tRNA by their cognate amino acid in the initial step of ribosome-dependent protein biosynthesis. FARSLA, also known as FRSA, CML33, FARSL or PheHA (phenylalanyl-tRNA synthetase, alpha subunit), is a member of the class-II aminoacyl-tRNA synthetase family and is highly expressed in proliferating cells of bone marrow. FARSLA is a cytoplasmic phenylalanine-tRNA synthetase that functions as a heterodimer consisting of a catalytic alpha-subunit and a regulatory beta-subunit. The alpha-subunit is responsible for forming the amino acid binding pocket, mediating the ATP/aminoacyl adenylate binding, and interacts with the acceptor stem of the tRNA. FARSLA functions in a cell cycle-dependent and differentiation-dependent manner.

Function:
FARSLA (Phenylalanyl-tRNA synthetase alpha chain) is an aminoacyl-tRNA synthetase. These are a class of enzymes that charge tRNAs with their cognate amino acids. Cytoplasmic phenylalanine-tRNA synthetase is a heterodimer consisting of a catalytic alpha subunit, FARSLA, and a regulatory beta subunit, FARSLB. This protein has been shown to be expressed in a tumor-selective and cell cycle stage- and differentiation-dependent manner, the first member of the tRNA synthetase family shown to exhibit this type of regulated expression.

Subcellular Location:
Cytoplasmic.

Similarity:
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

Database links:

Entrez Gene: 2193 Human

Entrez Gene: 66590 Mouse

Entrez Gene: 288917 Rat

Omim: 602918 Human

SwissProt: Q9Y285 Human

SwissProt: Q8C0C7 Mouse

SwissProt: Q505J8 Rat

Unigene: 23111 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
  氨基酰-tRNA合成酶是一类酶,在核糖体依赖的蛋白质生物合成的初始阶段,它们通过其同源氨基酸催化tRNA的特异性氨基酰化。FARSLA,又称FRSA、CML33、FARSL或PheHA(丙酰-tRNA合成酶,α亚基),是II类氨基酰-tRNA合成酶家族的成员,在骨髓增生细胞中高度表达。FARSLA是一种胞质丙氨酸-tRNA合成酶,其作为由催化性α亚基和调节性β亚基组成的异二聚体。α亚基负责形成氨基酸结合袋,介导ATP/氨基酰腺苷酸结合,并与tRNA的受体杆相互作用。FARSLA在细胞周期依赖性和分化依赖性中起作用。
   

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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