FITC标记的过氧化物酶体2抗体
产品名称: FITC标记的过氧化物酶体2抗体
英文名称: Anti-DECR2/FITC
产品编号: HZ-14240R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DECR2/FITC Conjugated antibody
FITC标记的过氧化物酶体2抗体
英文名称 | Anti-DECR2/FITC |
中文名称 | FITC标记的过氧化物酶体2抗体 |
别 名 | 2 4 dienoyl CoA reductase 2; 2 4 dienoyl CoA reductase 2 peroxisomal; 2; 4-dienoyl-CoA reductase 2; 4-dienoyl-CoA reductase; DECR 2; Decr2; DECR2_HUMAN; EC 1.3.1.34; pDCR; Peroxisomal 2 4 dienoyl CoA reductase; Peroxisomal 2; SDR17C1; Short chain dehydrogenase/reductase family 17C member 1. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 细胞类型标志物 新陈代谢 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Horse, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 31kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DECR2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: DECR2 is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2,4-dienoyl-CoA reductase protein subfamily. Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. DECR2 has also been shown to have catalytic activity towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA and short and medium chain 2,4-dienoyl-CoAs, suggesting that DECR2 is not a rate limiting step in the degradation of docosahexaenoic acid in the peroxisome. DECR2 is expressed as three isoforms produced by alternative splicing events. Function: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. Subunit: Monomer, dimer and oligomer. Subcellular Location: Peroxisome. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily. Database links: Entrez Gene: 26063 Human Entrez Gene: 26378 Mouse Entrez Gene: 64461 Rat SwissProt: Q9NUI1 Human SwissProt: Q9WV68 Mouse SwissProt: Q9Z2M4 Rat Unigene: 628831 Human Unigene: 655999 Human Unigene: 292869 Mouse Unigene: 144598 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
decr2是292氨基酸组成的短链脱氢酶/还原酶(SDR)蛋白家族和2,4 -二烯酰基-CoA还原酶蛋白亚家族。定位于过氧化物酶体β-氧化,decr2是催化2,4 -二烯酰基-CoA NADP依赖还原产生trans-3-enoyl-coa辅助酶。decr2也被证明对2,4,7,10,13,16,19-docosaheptaenoyl-coa和短链和中链2,4-dienoyl-coas具有催化活性,这表明decr2不是率在过氧化物酶体的二十二碳六烯酸降解的限速步骤。DECR2表示为三个异构体产生的选择性剪接事件。