Rabbit Anti-DECR2/FITC Conjugated antibody
|别 名||2 4 dienoyl CoA reductase 2; 2 4 dienoyl CoA reductase 2 peroxisomal; 2; 4-dienoyl-CoA reductase 2; 4-dienoyl-CoA reductase; DECR 2; Decr2; DECR2_HUMAN; EC 22.214.171.124; pDCR; Peroxisomal 2 4 dienoyl CoA reductase; Peroxisomal 2; SDR17C1; Short chain dehydrogenase/reductase family 17C member 1.|
|规格价格||100ul/2980元 购买 大包装/询价|
|说 明 书||100ul|
|研究领域||细胞生物 细胞类型标志物 新陈代谢|
|交叉反应||Human, Mouse, Rat, Horse,|
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
|分 子 量||31kDa|
|性 状||Lyophilized or Liquid|
|免 疫 原||KLH conjugated synthetic peptide derived from human DECR2|
|纯化方法||affinity purified by Protein A|
|储 存 液||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.|
|保存条件||Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.|
DECR2 is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2,4-dienoyl-CoA reductase protein subfamily. Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. DECR2 has also been shown to have catalytic activity towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA and short and medium chain 2,4-dienoyl-CoAs, suggesting that DECR2 is not a rate limiting step in the degradation of docosahexaenoic acid in the peroxisome. DECR2 is expressed as three isoforms produced by alternative splicing events.
Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
Monomer, dimer and oligomer.
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
Entrez Gene: 26063 Human
Entrez Gene: 26378 Mouse
Entrez Gene: 64461 Rat
SwissProt: Q9NUI1 Human
SwissProt: Q9WV68 Mouse
SwissProt: Q9Z2M4 Rat
Unigene: 628831 Human
Unigene: 655999 Human
Unigene: 292869 Mouse
Unigene: 144598 Rat
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
decr2是292氨基酸组成的短链脱氢酶/还原酶（SDR）蛋白家族和2,4 -二烯酰基-CoA还原酶蛋白亚家族。定位于过氧化物酶体β-氧化，decr2是催化2,4 -二烯酰基-CoA NADP依赖还原产生trans-3-enoyl-coa辅助酶。decr2也被证明对2,4,7,10,13,16,19-docosaheptaenoyl-coa和短链和中链2,4-dienoyl-coas具有催化活性，这表明decr2不是率在过氧化物酶体的二十二碳六烯酸降解的限速步骤。DECR2表示为三个异构体产生的选择性剪接事件。