FITC标记的DEF8蛋白抗体-抗体-抗体-生物在线
FITC标记的DEF8蛋白抗体

FITC标记的DEF8蛋白抗体

商家询价

产品名称: FITC标记的DEF8蛋白抗体

英文名称: Anti-DEF8/FITC

产品编号: HZ-14241R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

上海沪震实业有限公司
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  • 邮编 : 200612
  • 所在区域 : 上海
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 Rabbit Anti-DEF8/FITC Conjugated antibody

FITC标记的DEF8蛋白抗体

 

英文名称 Anti-DEF8/FITC
中文名称 FITC标记的DEF8蛋白抗体
别    名 DEF-8; Def8; Def 8; DEFI8_HUMAN; Differentially expressed in FDCP 8 homolog; FLJ20186; MGC104349.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DEF8
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
DEF8 is a 512 amino acid protein that is expressed at highest levels in peripheral leukocytes. It is expressed as five isoforms as a result of alternative splicing events. The gene encoding DEF8 maps to chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition that may involve the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

Similarity:
Belongs to the DEF8 family.
Contains 2 phorbol-ester/DAG-type zinc fingers.

Database links:

Entrez Gene: 54849 Human

SwissProt: Q6ZN54 Human

Unigene: 62771 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
   

DEF8是一种在外周血白细胞中最高表达的512氨基酸蛋白。它作为替代剪接事件的结果被表示为五种异构体。编码DEF8的基因定位于染色体16,在大约9000万碱基对中编码900多个基因,占人类细胞DNA的近3%,并且与多种遗传病有关。罕见的Rubinstein-Taybi综合征与16号染色体有关,克罗恩病也是,一种可能涉及NOD2基因的胃肠道炎症状态。系统性红斑狼疮和许多其它与染色体16的着丝粒周区相关的自身免疫性疾病导致SLC5A11被鉴定为潜在的自身免疫调节剂。