FITC标记的防御素β-109/β-defensin 109抗体
产品名称: FITC标记的防御素β-109/β-defensin 109抗体
英文名称: Anti-DEFB109/FITC
产品编号: HZ-14243R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DEFB109/FITC Conjugated antibody
FITC标记的防御素β-109/β-defensin 109抗体
英文名称 | Anti-DEFB109/FITC |
中文名称 | FITC标记的防御素β-109/β-defensin 109抗体 |
别 名 | Beta defensin 109; DB109_HUMAN; DEFB109 Beta defensin 109; Defensin beta 109. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 发育生物学 细菌及病毒 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 7.4kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DEFB109 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Beta-defensins are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. The family of Beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many Beta-defensins also are involved in sperm maturation and capacitation. Beta-defensin 109 is an 87 amino acid secreted protein that is notably expressed on the ocular surface and is found in reduced levels in microbial infection, therefore suggesting that this particular Beta-defensin is unlikely to have a major antimicrobial effect. Function: DEFB109 belongs to the beta defensin family. It has antibacterial activity. Subcellular Location: Secreted Similarity: Belongs to the beta-defensin family. Database links: Entrez Gene: 100286963 Human Entrez Gene: 641517 Human SwissProt: Q30KR1 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
β-防御素是一种具有广谱抗菌活性的小型阳离子肽,对多种包膜病毒、真菌和细菌均有抑制作用。在几种上皮细胞的粘膜上皮和中性粒细胞中,β防御素是发育调节的。β-防御素蛋白家族有一个共同的防御主题,由多个半胱氨酸残基和一个高度保守的三级结构。除了在宿主免疫防御的一个重要的角色,许多β-防御素也参与了精子成熟和获能。β-防御素109是一个87个氨基酸的分泌蛋白,特别表现在眼表面是水平降低的微生物感染,因此这个特定的β-防御素是不可能有一个主要的抗菌效果。