FITC标记的微管蛋白δ1/δ Tubulin抗体
产品名称： FITC标记的微管蛋白δ1/δ Tubulin抗体
英文名称： Anti-Delta 1 Tubulin/FITC
产品编号： HZ-14263R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
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- 邮编 : 200612
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Rabbit Anti-Delta 1 Tubulin/FITC Conjugated antibody
FITC标记的微管蛋白δ1/δ Tubulin抗体
| 英文名称 | Anti-Delta 1 Tubulin/FITC |
| 中文名称 | FITC标记的微管蛋白δ1/δ Tubulin抗体 |
| 别 名 | Delta tubulin; Delta-tubulin; FLJ12709; TBD_HUMAN; TUBD; TUBD1; Tubulin delta chain. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 51kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Delta 1 Tubulin |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Tubulin is a major cytoskeleton component that has five distinct forms, designated a, b, g, d and e tubulin. a and b tubulins form heterodimers which multimerize to form a microtubule filament. Multiple b Tubulin isoforms (b1, b2, b3, b4, b5, b6 and b8) have been characterized and are expressed in mammalian tissues. b1 and b4 are present throughout the cytosol, b2 is present in the nuclei and nucleoplasm, and b3 is a neuron-specific cytoskeletal protein. GammaTubulin forms the gammasome, which is required for nucleating microtubule filaments at the centrosome. Both d Tubulin and Delta Tubulin are associated with the centrosome. Gamma Tubulin is a homolog of the Chlamydomonas Gamma Tubulin Uni3 and is found in association with the centrioles, whereas e Tubulin localizes to the pericentriolar material. Delta Tubulin exhibits a cell cycle-specific pattern of localization; first associating with only the older of the centrosomes in a newly duplicated pair, and later associating with both centrosomes. Function: In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head. Subcellular Location: Cytoplasm > cytoskeleton > centrosome > centriole. Cytoplasm. Nucleus. Associated with centrioles. Both cytoplasmic and nuclear. Similarity: Belongs to the tubulin family. Database links: Entrez Gene: 51174 Human Omim: 607344 Human SwissProt: Q9UJT1 Human Unigene: 463638 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
微管蛋白是一种主要的细胞骨架成分，具有五种不同的形式，被命名为A、B、G、D和E微管蛋白。A和B微管蛋白形成异源二聚体，多聚体形成微管丝。多个B Tubulin亚型（B1，B2，B3，B4，B5，B6和B8）已被表征并在哺乳动物组织中表达。B1和B4存在于细胞质中，B2存在于细胞核和核质中，B3是神经元特异性的细胞骨架蛋白。γ-球蛋白形成γ染色体，这是中心体微管丝成核所必需的。d Tubulin和δ微管蛋白与中心体相关。γ-微管蛋白是衣藻γ-微管蛋白Un3的同系物，与中心粒相关，而鄂土布琳定位于近中心粒材料。δ微管蛋白具有一种细胞周期特异性的定位模式，首先与一个新的复制对中的中心体相关联，然后与两个中心体相关联。