FITC标记的二酰基甘油酰基转移酶2样蛋白4抗体
产品名称： FITC标记的二酰基甘油酰基转移酶2样蛋白4抗体
英文名称： Anti-DGAT2L4/FITC
产品编号： HZ-14290R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DGAT2L4/FITC Conjugated antibody
FITC标记的二酰基甘油酰基转移酶2样蛋白4抗体
| 英文名称 | Anti-DGAT2L4/FITC |
| 中文名称 | FITC标记的二酰基甘油酰基转移酶2样蛋白4抗体 |
| 别 名 | Acyl CoA wax alcohol acyltransferase 2; acyl-CoA retinol O-fatty-acyltransferase; ARAT; AWAT2; DC4; Diacylglycerol O acyltransferase 2 like 4; Diacylglycerol O acyltransferase candidate 4; diacylglycerol O-acyltransferase 2-like protein 4; hWS; Long chain alcohol O fatty acyltransferase 2; MFAT; Multifunctional O acyltransferase; retinol O-fatty-acyltransferase; Wax synthase 2; Wax synthase; WS. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 38kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DGAT2L4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes an enzyme belonging to the diacylglycerol acyltransferase family. This enzyme produces wax esters by the esterification of long chain (or wax) alcohols with acyl-CoA-derived fatty acids. It functions in lipid metabolism in the skin, mostly in undifferentiated peripheral sebocytes. This enzyme may also have acyl-CoA:retinol acyltransferase activities, where it catalyzes the synthesis of diacylglycerols and retinyl esters. [provided by RefSeq, May 2010] Function: Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. May also have 2 acylglycerol O acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters; however this activity is unclear in vivo. Subcellular Location: Endoplasmic reticulum membrane; Multipass membrane protein. Tissue Specificity: Abundant in tissues rich in sebaceous glands such as the preputial gland and eyelid. Highly expressed in skin, where it is primarily restricted to undifferentiated peripheral sebocytes. Also expressed at lower level in other tissues except pancreas. Similarity: Belongs to the diacylglycerol acyltransferase family. Database links: Entrez Gene: 158835 Human Entrez Gene: 245532 Mouse Entrez Gene: 302425 Rat SwissProt: Q6E213 Human SwissProt: Q6E1M8 Mouse Unigene: 661507 Human Unigene: 118171 Mouse Unigene: 220750 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码属于甘油二酯酰基转移酶家族的酶。这种酶通过长链（或蜡）醇与酰基辅酶A衍生的脂肪酸的酯化产生蜡酯。它在皮肤中的脂质代谢中起作用，主要是在未分化的周围皮脂细胞中。该酶还具有酰基辅酶A:视黄醇酰基转移酶活性，催化合成二酰甘油和视黄醇酯。[ RefSeq，2010年5月提供]