FITC标记的甘油二酯激酶β/DGK-β抗体
产品名称： FITC标记的甘油二酯激酶β/DGK-β抗体
英文名称： Anti-DGKB/FITC
产品编号： HZ-14295R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-DGKB/FITC Conjugated antibody
FITC标记的甘油二酯激酶β/DGK-β抗体
| 英文名称 | Anti-DGKB/FITC |
| 中文名称 | FITC标记的甘油二酯激酶β/DGK-β抗体 |
| 别 名 | 90 kDa diacylglycerol kinase; DAG kinase beta; DAGK2; DGK; DGK B; DGK beta; DGK-beta; Dgkb; DGKB_HUMAN; Diacylglycerol kinase beta (90kD); Diacylglycerol kinase beta 90kDa; Diacylglycerol kinase beta; Diglyceride kinase beta; KIAA0718. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 新陈代谢 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 91kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DGKB |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008] Function: Exhibits high phosphorylation activity for long-chain diacylglycerols. Subcellular Location: Cytoplasm. Similarity: Belongs to the eukaryotic diacylglycerol kinase family. Contains 1 DAGKc domain. Contains 2 EF-hand domains. Contains 2 phorbol-ester/DAG-type zinc fingers. Database links: Entrez Gene: 1607 Human Entrez Gene: 217480 Mouse Omim: 604070 Human SwissProt: Q9Y6T7 Human SwissProt: Q6NS52 Mouse Unigene: 567255 Human Unigene: 126525 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Diacylglycerol kinases（DGKs）是第二信使二酰基甘油（DAG）细胞内浓度的调节者，因此在细胞过程中起关键作用。已经鉴定出九种哺乳动物的同种型，它们是由单独的基因编码的。哺乳动物DGK同工酶含有保守的催化（激酶）结构域和富含半胱氨酸的结构域（CRD）。由该基因编码的蛋白质是甘油二酯激酶，β同种型。已经发现了两个交替剪接转录变体。