FITC标记的甘油二酯激酶δ/DGK-δ抗体上海沪震实业有限公司

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产品名称: FITC标记的甘油二酯激酶δ/DGK-δ抗体
英文名称: Anti-DGKD/FITC
抗体货号: HZ-14296R-FITC
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/10/12 8:22:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
地址:
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邮编:
200612
电话:
021-60345367
传真:
021-31320307
联系人:
陈先生
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上海·中国-上海
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产品详细描述

 Rabbit Anti-DGKD/FITC Conjugated antibody

FITC标记的甘油二酯激酶δ/DGK-δ抗体

 

英文名称 Anti-DGKD/FITC
中文名称 FITC标记的甘油二酯激酶δ/DGK-δ抗体
别    名 130 kDa diacylglycerol kinase; DAG kinase delta; DGK delta; DGK-delta; DGKD; DGKD_HUMAN; DGKdelta; Diacylglycerol kinase delta; Diglyceride kinase delta; FLJ26930; KIAA0145.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 134kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DGKD
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a cytoplasmic enzyme that phosphorylates diacylglycerol to produce phosphatidic acid. Diacylglycerol and phosphatidic acid are two lipids that act as second messengers in signaling cascades. Their cellular concentrations are regulated by the encoded protein, and so it is thought to play an important role in cellular signal transduction. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Function:
May function as signaling molecule. Isoform 2 may be involved in cell growth and tumorigenesis. Involved in clathrin-dependent endocytosis.

Subcellular Location:
Cytoplasm and Membrane.

Tissue Specificity:
Isoform 2 is ubiquitously expressed also in tumor tissues. Isoform 1 is expressed in ovary, spleen and some tumor-derived cells.

Post-translational modifications:
Isoform 1 H domain is phosphorylated.

Similarity:
Belongs to the eukaryotic diacylglycerol kinase family.
Contains 1 DAGKc domain.
Contains 1 PH domain.
Contains 2 phorbol-ester/DAG-type zinc fingers.
Contains 1 SAM (sterile alpha motif) domain.

Database links:

Entrez Gene: 8527 Human

Omim: 601826 Human

SwissProt: Q16760 Human

Unigene: 471675 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

该基因编码***酸化二酰甘油以产生***脂酸的细胞质酶。二酰甘油和***脂酸是两种脂质,在信号级联中起第二信使的作用。它们的细胞浓度受编码蛋白的调节,因此被认为在细胞信号转导中起重要作用。选择性剪接结果在两个转录变体中编码不同的亚型。[ RefSeq,JUL 2008 ]

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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