FITC标记的甘油二酯激酶δ/DGK-δ抗体
产品名称： FITC标记的甘油二酯激酶δ/DGK-δ抗体
英文名称： Anti-DGKD/FITC
产品编号： HZ-14296R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DGKD/FITC Conjugated antibody
FITC标记的甘油二酯激酶δ/DGK-δ抗体
| 英文名称 | Anti-DGKD/FITC |
| 中文名称 | FITC标记的甘油二酯激酶δ/DGK-δ抗体 |
| 别 名 | 130 kDa diacylglycerol kinase; DAG kinase delta; DGK delta; DGK-delta; DGKD; DGKD_HUMAN; DGKdelta; Diacylglycerol kinase delta; Diglyceride kinase delta; FLJ26930; KIAA0145. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 信号转导 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 134kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DGKD |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a cytoplasmic enzyme that phosphorylates diacylglycerol to produce phosphatidic acid. Diacylglycerol and phosphatidic acid are two lipids that act as second messengers in signaling cascades. Their cellular concentrations are regulated by the encoded protein, and so it is thought to play an important role in cellular signal transduction. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Function: May function as signaling molecule. Isoform 2 may be involved in cell growth and tumorigenesis. Involved in clathrin-dependent endocytosis. Subcellular Location: Cytoplasm and Membrane. Tissue Specificity: Isoform 2 is ubiquitously expressed also in tumor tissues. Isoform 1 is expressed in ovary, spleen and some tumor-derived cells. Post-translational modifications: Isoform 1 H domain is phosphorylated. Similarity: Belongs to the eukaryotic diacylglycerol kinase family. Contains 1 DAGKc domain. Contains 1 PH domain. Contains 2 phorbol-ester/DAG-type zinc fingers. Contains 1 SAM (sterile alpha motif) domain. Database links: Entrez Gene: 8527 Human Omim: 601826 Human SwissProt: Q16760 Human Unigene: 471675 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码磷酸化二酰甘油以产生磷脂酸的细胞质酶。二酰甘油和磷脂酸是两种脂质，在信号级联中起第二信使的作用。它们的细胞浓度受编码蛋白的调节，因此被认为在细胞信号转导中起重要作用。选择性剪接结果在两个转录变体中编码不同的亚型。[ RefSeq，JUL 2008 ]