FITC标记的甘油二酯激酶ζ/DGK-ζ抗体上海沪震实业有限公司

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产品名称: FITC标记的甘油二酯激酶ζ/DGK-ζ抗体
英文名称: Anti-DGKZ/FITC
抗体货号: HZ-14301R-FITC
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/10/12 8:26:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-DGKZ/FITC Conjugated antibody 

FITC标记的甘油二酯激酶ζ/DGK-ζ抗体

 

英文名称 Anti-DGKZ/FITC
中文名称 FITC标记的甘油二酯激酶ζ/DGK-ζ抗体
别    名 DAG kinase zeta; DAGK5; DAGK5 PEN; DAGK6; DGK ZETA; DGK-zeta; Dgkz; DGKZ_HUMAN; Diacylglycerol kinase zeta; Diglyceride kinase zeta; hDGKzeta.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Guinea Pig, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 124kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DGKZ
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2010]

Function:
Displays a strong preference for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. Isoform 2 but not isoform 1 regulates RASGRP1 activity.

Subcellular Location:
Cytoplasm. Nucleus. Cell membrane.

Tissue Specificity:
Highest levels in brain, and substantial levels in skeletal muscle, heart, and pancreas. Isoform 1 is predominantly expressed in muscle.

Post-translational modifications:
Phosphorylation of the MARCKS homology domain by PKC reduces nuclear accumulation of DGK-zeta.

Similarity:
Belongs to the eukaryotic diacylglycerol kinase family.
Contains 2 ANK repeats.
Contains 1 DAGKc domain.
Contains 2 phorbol-ester/DAG-type zinc fingers.

Database links:

Entrez Gene: 8525 Human

Entrez Gene: 423197 Chicken

Entrez Gene: 483635 Dog

Entrez Gene: 100050499 Horse

Entrez Gene: 104418 Mouse

Entrez Gene: 81821 Rat

Omim: 601441 Human

SwissProt: Q13574 Human

SwissProt: Q80UP3 Mouse

SwissProt: O08560 Rat

Unigene: 502461 Human

Unigene: 314923 Mouse

Unigene: 11208 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

该基因编码的蛋白属于真核甘油二酯激酶家族。它可能通过调节细胞内信号级联和信号转导中的二酰甘油水平来减弱蛋白激酶C的活性。在该位点发生选择性剪接,并鉴定了编码不同亚型的多个转录变体。[ RefSeq,2010月11日]

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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