FITC标记的DHX8蛋白抗体-抗体-抗体-生物在线
FITC标记的DHX8蛋白抗体

FITC标记的DHX8蛋白抗体

商家询价

产品名称: FITC标记的DHX8蛋白抗体

英文名称: Anti-DHX8/FITC

产品编号: HZ-14324R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

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 Rabbit Anti-DHX8/FITC Conjugated antibody

FITC标记的DHX8蛋白抗体

 

英文名称 Anti-DHX8/FITC
中文名称 FITC标记的DHX8蛋白抗体
别    名 ATP dependent RNA helicase DHX8; ATP-dependent RNA helicase dhx8; DDX 8; DDX8; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8 (RNA helicase); DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8; DEAD/H box polypeptide 8; DEAH (Asp Glu Ala His) box polypeptide 8; DEAH box polypeptide 8; DEAH box protein 8; DHX 8; dhx8; DHX8_HUMAN; HRH 1; HRH1; PRP 22; PRP22; PRPF 22; PRPF22; RNA helicase HRH 1; RNA helicase HRH1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  细胞分化  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 139kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DHX8
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is highly homologous to yeast Prp22. This protein facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. [provided by RefSeq, Jul 2008]

Function:
Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.

Subunit:
Identified in the spliceosome C complex. Interacts with ARRB2; the interaction is detected in the nucleus upon OR1D2 stimulation.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
Contains 1 S1 motif domain.

Database links:

Entrez Gene: 1659 Human

Entrez Gene: 217207 Mouse

Entrez Gene: 287727 Rat

Omim: 600396 Human

SwissProt: Q14562 Human

SwissProt: A2A4P0 Mouse

Unigene: 463105 Human

Unigene: 28186 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

死盒蛋白,其特征在于保守的基序ASP Glu ALA-ASP(死亡),是假定的RNA解旋酶。它们涉及许多涉及RNA二级结构改变的细胞过程,如翻译起始、核和线粒体剪接、核糖体和剪接体组装。根据它们的分布模式,该家族的一些成员被认为参与胚胎发生、精子发生和细胞生长和分裂。该基因编码一个与酵母PRP22高度同源的死盒蛋白。这种蛋白质通过剪接体RNA的释放促进了剪接mRNA的核输出。[ RefSeq,JUL 2008 ]