FITC标记的红细胞膜蛋白STOM抗体上海沪震实业有限公司

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产品名称: FITC标记的红细胞膜蛋白STOM抗体
英文名称: Anti-STOM/FITC
抗体货号: HZ-10443R-FITC
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/10/12 8:48:00
详细资料:  实验方法技术资料
浏览人数:6
诚信指数:1084点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
地址:
上海市杨浦区密云路1018号复旦科技园808室
邮编:
200612
电话:
021-60345367
传真:
021-31320307
联系人:
陈先生
所在区域:
上海·中国-上海
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产品详细描述

 Rabbit Anti-STOM/FITC Conjugated antibody

FITC标记的红细胞膜蛋白STOM抗体

 

英文名称 Anti-STOM/FITC
中文名称 FITC标记的红细胞膜蛋白STOM抗体
别    名 BND7; EPB7; EPB72; Erythrocyte band 7 integral membrane protein; Erythrocyte membrane protein band 7.2 (stomatin); Protein 7.2b; STOM; STOM_HUMAN; Stomatin.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  通道蛋白  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human STOM
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Function:
Thought to regulate cation conductance. May regulate ACCN1 and ACCN3 gating.

Subunit:
Homooligomer containing between 9 and 12 monomers. Interacts with ASIC1, ASIC2 and ASIC3. Interacts with LANCL1.

Subcellular Location:
Cell membrane. Cell membrane. Melanosome. Exposed on the cytoplasmic surface of the membrane. Associated with lipid rafts. Concentrates preferentially in plasma membrane protrusions and in a juxta-nuclear region which may represent Golgi-derived vesicles. Colocalizes with actin. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the band 7/mec-2 family.

Database links:

Entrez Gene: 2040 Human

Entrez Gene: 13830 Mouse

Entrez Gene: 296655 Rat

Omim: 133090 Human

SwissProt: P27105 Human

SwissProt: P54116 Mouse

Unigene: 253903 Human

Unigene: 295284 Mouse

Unigene: 229238 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

该基因编码一个高度保守的整体膜蛋白家族的成员。编码蛋白定位于红细胞和其他细胞类型的细胞膜,在那里它可能调节离子通道和转运体。编码蛋白的定位丧失与遗传性口形红细胞增多症有关,这是溶血性贫血的一种形式。在第6号染色体上有这种基因的假基因。选择性剪接导致多个转录变体。[ RefSeq,JUL 2012 ]

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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