FITC标记的微粒体谷胱甘肽S转移酶1抗体
产品名称： FITC标记的微粒体谷胱甘肽S转移酶1抗体
英文名称： Anti-MGST1/FITC
产品编号： HZ-10447R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
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Rabbit Anti-MGST1/FITC Conjugated antibody
FITC标记的微粒体谷胱甘肽S转移酶1抗体
| 英文名称 | Anti-MGST1/FITC |
| 中文名称 | FITC标记的微粒体谷胱甘肽S转移酶1抗体 |
| 别 名 | MGST1; Glutathione S transferase 12; Microsomal glutathione transferase 1; GST12; MGST 1; MGST; MGST1; MGST1_HUMAN; Microsomal glutathione S-transferase 1; Microsomal GST 1; Microsomal GST-1; Microsomal GST-I. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 信号转导 Alzheimer's |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 17kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MGST1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene. [provided by RefSeq, May 2012] Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity. Subcellular Location: Microsome. Mitochondrion outer membrane. Endoplasmic reticulum membrane. Tissue Specificity: Highly expressed in liver. Post-translational modifications: Peroxynitrite induces nitration at Tyr-93 which activates the enzyme. Similarity: Belongs to the MAPEG family. Database links: Entrez Gene: 4257 Human Entrez Gene: 56615 Mouse Entrez Gene: 171341 Rat Omim: 138330 Human SwissProt: P10620 Human SwissProt: Q91VS7 Mouse SwissProt: P08011 Rat Unigene: 389700 Human Unigene: 14796 Mouse Unigene: 2580 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
MAPG（膜相关蛋白在Eicosanoid和谷胱甘肽代谢）家族由六个人类蛋白组成，其中两个参与白三烯和前列腺素E的产生，炎症的重要介质。其他家族成员，显示谷胱甘肽S-转移酶和过氧化物酶活性，参与细胞防御，以对抗毒性、致癌和药理活性的亲电化合物。该基因编码一种催化谷胱甘肽与亲电体结合和脂质过氧化物的还原的蛋白质。这种蛋白质定位于内质网和线粒体膜外，据认为可以保护这些膜免受氧化应激。已经发现了一些转录本变体，一些非蛋白编码和一些蛋白质编码。[ RefSeq，2012年5月提供]