FITC标记的1号染色体开放阅读框73抗体上海沪震实业有限公司

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产品名称: FITC标记的1号染色体开放阅读框73抗体
英文名称: Anti-INTS7/C1orf73/FITC
抗体货号: HZ-14337R-FITC
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/12/8 14:49:00
详细资料:  实验方法技术资料
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诚信指数:1084点
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-INTS7/C1orf73/FITC Conjugated antibody 

FITC标记的1号染色体开放阅读框73抗体

 

英文名称 Anti-INTS7/C1orf73/FITC
中文名称 FITC标记的1号染色体开放阅读框73抗体
别    名 INTS7; 5930412E23Rik; DKFZP434B168; C1orf73; Chromosome 1 open reading frame 73; chunp6916; DKFZp434B168; FLJ10736; FLJ12447; Int7; INT7_HUMAN; integrator complex subunit 7; INTS7; Ints7 integrator complex subunit 7; OTTHUMP00000035211; RGD1308014.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 107kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human INTS7/C1orf73
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Function:
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Plays a role in DNA damage response (DDR) signaling during the S phase.

Subunit:
Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12. Interacts with NABP2.

Subcellular Location:
Nucleus. Chromosome. Localizes to sites of DNA damage in a H2AX-independent manner.

Similarity:
Belongs to the Integrator subunit 7 family.

Database links:

Entrez Gene: 25896 Human

Entrez Gene: 421374 Chicken

Omim: 611350 Human

SwissProt: Q5ZL91 Chicken

SwissProt: Q1RMS6 Cow

SwissProt: Q9NVH2 Human

Unigene: 369285 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

该基因编码积分器复合体的亚基。整合子复合物与RNA聚合酶II的C端结构域相关联,介导小核RNA U1和U2的3′端加工。另一种编码多个异构体的剪接转录变体已被观察到该基因。[ RefSeq提供,DEC 2010 ]

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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