FITC标记的肺癌和食道癌缺失基因1抗体上海沪震实业有限公司

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产品名称: FITC标记的肺癌和食道癌缺失基因1抗体
英文名称: Anti-DLEC1/FITC
抗体货号: HZ-14341R-FITC
产品规格: 100ul
级    别: , , 分析纯, , 分析纯,
产品产地: 中国/上海
品牌商标: HZbscience
价    格: 2980元
抗原: Rabbit
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: 
FITCconjugate:FITC
应用范围: ICC=1:50-200 IF=1:50-200
更新时间: 2018/10/12 9:04:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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上海沪震实业有限公司
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产品详细描述

 Rabbit Anti-DLEC1/FITC Conjugated antibody

FITC标记的肺癌和食道癌缺失基因1抗体

 

英文名称 Anti-DLEC1/FITC
中文名称 FITC标记的肺癌和食道癌缺失基因1抗体
别    名 Deleted in lung and esophageal cancer 1; Deleted in lung and esophageal cancer 1 transcript varient 2; Deleted in lung and esophageal cancer protein 1; Deleted in lung cancer protein 1; DLC 1; Dlc-1; DLC1; Dlec1; DLEC1_HUMAN; F56.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 196kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DLEC1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins. Aberrant transcription of this gene may be involved in carcinogenesis of the lung, esophagus, and kidney. [provided by RefSeq, Jul 2008]

Function:
May act as a tumor suppressor by inhibiting cell proliferation.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in all tissues examined. Expression is highest in prostate and testis.

DISEASE:
Note=DLEC1 silencing due to promoter methylation and aberrant transcription are implicated in the development of different cancers, including esophageal, renal and lung cancers.

Database links:

Entrez Gene: 9940 Human

Omim: 604050 Human

SwissProt: Q9Y238 Human

Unigene: 714499 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

该基因包含37个外显子,跨度约59-kb,位于各种癌症中通常缺失的3p22-p21.3染色体段。已经观察到一些选择性剪接的转录本,它们含有中断的编码区,并且可能编码非功能性蛋白质。该基因的异常转录可能参与肺癌、食道和肾脏的癌变过程。[ RefSeq,JUL 2008 ]

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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