FITC标记的磷酸化肝癌缺失基因1抗体-抗体-抗体-生物在线
FITC标记的磷酸化肝癌缺失基因1抗体

FITC标记的磷酸化肝癌缺失基因1抗体

商家询价

产品名称: FITC标记的磷酸化肝癌缺失基因1抗体

英文名称: Anti-phospho-DLC1 (Ser567)/FITC

产品编号: HZ-14339R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

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 Rabbit Anti-phospho-DLC1 (Ser567)/FITC Conjugated antibody 

FITC标记的磷酸化肝癌缺失基因1抗体

 

英文名称 Anti-phospho-DLC1 (Ser567)/FITC
中文名称 FITC标记的磷酸化肝癌缺失基因1抗体
别    名 p-DLC1 (Ser567); DLC1 (phospho S567); p-DLC1 (phospho S567); ARHGAP 7; ARHGAP7; Deleted in liver cancer 1; Deleted in liver cancer 1 protein; DLC 1; Dlc-1; DLC1; FLJ21120; HP; HP protein; KIAA1723; p122 RhoGAP; RHG07_HUMAN; Rho GTPase activating protein 7; Rho GTPase-activating protein 7; Rho type GTPase activating protein 7; Rho-type GTPase-activating protein 7; StAR related lipid transfer protein 12; StAR-related lipid transfer protein 12; STARD 12; StARD12; START domain containing protein 12; START domain-containing protein 12.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 肿瘤  细胞生物  信号转导  细胞类型标志物  表观遗传学  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 171kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human DLC1 around the phosphorylation site of Ser567
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]

Function:
Functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus.

Similarity:
Contains 1 Rho-GAP domain.
Contains 1 SAM (sterile alpha motif) domain.
Contains 1 START domain.

Database links:

Entrez Gene: 10395 Human

Omim: 604258 Human

SwissProt: Q96QB1 Human

Unigene: 134296 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

该基因编码GTP酶激活蛋白(GAP),它是rhoGAP蛋白家族的成员,在调节小GTP结合蛋白中起作用。GAP家族蛋白参与调节细胞骨架变化的细胞过程的信号通路。该基因在许多常见癌症(包括前列腺癌、肺癌、结肠直肠癌和乳腺癌)中作为肿瘤抑制基因发挥作用。由于选择性启动子和选择性剪接,已经发现了该基因的多个转录体变体。