FITC标记的穿膜蛋白DLK2抗体
产品名称： FITC标记的穿膜蛋白DLK2抗体
英文名称： Anti-DLK2/FITC
产品编号： HZ-14342R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
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Rabbit Anti-DLK2/FITC Conjugated antibody
FITC标记的穿膜蛋白DLK2抗体
| 英文名称 | Anti-DLK2/FITC |
| 中文名称 | FITC标记的穿膜蛋白DLK2抗体 |
| 别 名 | AI413481; Delta like 2 homolog; Delta like protein 2; delta-like 2 homolog (Drosophila); DLK 2; DLK-2; Dlk2; DLK2_HUMAN; EGF like domain containing protein 9; EGF like domain multiple 9; EGF-like protein 9; EGFL 9; EGFL9; Epidermal growth factor-like protein 9; MGC111055; MGC2487; Multiple EGF like domain protein 9; OTTHUMP00000016449; OTTHUMP00000016451; Protein delta homolog 2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 生长因子和激素 结合蛋白 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 38kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DLK2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: DLK2 is a 383 amino acid single-pass transmembrane protein with six tandem EGF-like repeats in the putative extracellular domain, which is characteristic of the EGF-like protein family. DLK2 shares nearly identical structural features with DLK, suggesting that it may function in a similar way. Like DLK, DLK2 affects adipogenesis of 3T3-L1 preadipocytes and mesenchymal C3H10T1/2 cells, yet it does so in an opposite way to that of DLK. Also, expression of DLK and DLK2 are inversely correlated and changes in expression of one gene will affect the expression levels of the other. Therefore, it is likely that adipogenesis is modulated by the coordinated expression of DLK and DLK2. There are two isoforms of DLK2 that are produced as a result of alternative splicing events. Function: Regulates adipogenesis. Subcellular Location: Membrane. Similarity: Contains 6 EGF-like domains. Database links: Entrez Gene: 65989 Human Entrez Gene: 106565 Mouse SwissProt: Q6UY11 Human SwissProt: Q8K1E3 Mouse Unigene: 337251 Human Unigene: 23633 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
DLK2是一个383个氨基酸的单程跨膜蛋白，在细胞外结构域有6个串联的EGF样重复序列，是EGF样蛋白家族的特征。DLK2与DLK具有几乎相同的结构特征，表明它可以以类似的方式发挥作用。与DLK一样，DLK2影响3T3-L1前脂肪细胞和间充质C3H10T1/2细胞的脂肪生成，但其作用与DLK相反。此外，DLK和DLK2的表达是反向相关的，一个基因的表达变化将影响另一个基因的表达水平。因此，脂肪生成很可能是由DLK和DLK2的协同表达调节的。DLK2的两种异构体是作为选择性剪接事件的结果而产生的。